85047-9

MBL by meropenem to meropenem-EDTA IC ratio [Presence] by ARD gradient strip

Active

Term Description

This term is used to report the presence or absence of metallo beta-lactamase (MBL) enzymes based on inhibitory concentrations of meropenem and meropenem+EDTA. This term was created for, but is not limited in use to, bioMerieux's ETEST MBL assay.

Part Descriptions

LP232456-6 Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
Metallo beta-lactamase (MBL) enzymes are resistance enzymes whose activity is dependent on divalent cations such as zinc or cadmium, so that they can be inhibited by metal chelators such as EDTA. The presence of MBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as imipenem or meropenem, with the IC of that antimicrobial plus EDTA. Source: Regenstrief LOINC

LP234471-3 Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio:PrThr:Pt:Isolate:Ord:Gradient strip ARD
Long Common Name: MBL by meropenem to meropenem-EDTA IC ratio [Presence] by ARD gradient strip
Short Name: MBL mero + mer-EDTA IC rto Islt Ql Grad
Display Name: MBL by meropenem to meropenem-EDTA IC ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha Get Info: MBL by Meropenem to Meropenem-EDTA IC Ratio

Part Model Get Info

Component
Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
LP232456-6
- Analyte
  Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
  LP232456-6
  - Component Numerator
    Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
    LP232456-6
    - Component Numerator Core
      Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
      LP232456-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Gradient strip ARD
LP234471-3

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.58
Last Updated: Version 2.58 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Metalo-beta-laktamáza (MBL) pomocí poměru inhibiční koncentrace meropenemu k meropenemu-EDTA:Přítomnost nebo práh:Časový bod:Izolát:Ordinální:Testovací proužek s gradientem k detekci antimikrobiální rezistence
el-GR	Greek (Greece)	Αναλογία ανασταλτικής συγκέντρωσης μεταλλο-β-λακταμάσης από μεροπενέμη προς μεροπενέμη+αιθυλενοδιαμινοτετραοξικό οξύ:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Λωρίδα με διαβαθμίσεις ARD Synonyms: ABXBACT Ord PrThr Pt Αναλογία ανασταλτικής συγκέντρωσης μεταλλο-β-λακταμάσης από μεροπενέμη προς μεροπενέμη+αιθυλενοδιαμινοτετραοξικό οξύ Απομονωμένο στέλεχος Βήτα λακταμάση Λωρίδα με διαβαθμίσεις Λωρίδα με διαβαθμίσεις ARD Μεροπενέμη
es-ES	Spanish (Spain)	ESBL para la concentración inhibitoria de meropenem frente a la de meropenem-EDTA:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.
es-MX	Spanish (Mexico)	Relación de concentración inhibidora de metalo betalactamasa por meropenem a meropenem + EDTA:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
fr-FR	French (France)	Ratio CMI métallo bêta lactamase méropénème/EDTA:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-IT	Italian (Italy)	Rapporto concentrazione inibitoria metallo beta-lattamasi mediante meropenem/imeropenem+EDTA:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD Synonyms: Gradiente striscia (E-test) Presenza o Soglia Punto nel tempo (episodio) Rapporto IC MBL mediante meropenem/meropenem+EDTA Striscia di gradiente per detezione resistenza ant Suscettibilità agli antibiotici
pl-PL	Polish (Poland)	Metalo beta-laktamazy przez meropenem do meropenemu+EDTA wskaźnik stężenia hamującego:granica wykrywalności:punkt w czasie:izolat:uporządkowany:pasek gradientowy na środki przeciwdrobnoustrojowe Synonyms: Wskaźnik stężenia hamującego metalo-beta-laktamazy (MBL) przez meropenem i mieszaninę meropenemu z EDTA β-laktamaza
zh-CN	Chinese (China)	美罗培南相对于美罗培南+EDTA抑菌浓度比值法金属 beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法 Synonyms: ARD 梯度胶条法;E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条;ARD;antimicrobial resistance detection B Betalactamase Beta-内酰胺酶 B-Lactamase B-内酰胺酶 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 β β内酰胺酶 β-内酰胺酶依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分离物;分离菌;分离菌株;隔离种群存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间美洛培南美罗培南（美洛培南）相对于（与、相对）美罗培南（美洛培南）+EDTA（乙二胺四乙酸、依地酸、乙二胺四醋酸法）抑菌浓度（抑制浓度、IC）比值（比例、比、比率）法金属 beta 内酰胺酶（金属β内酰胺酶、金属β-内酰胺酶、MBL）;美罗培南相对于美罗培南+EDTA抑菌浓度比值法 MBL 贝塔

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85047-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.