Version 2.80

Term Description

This term is used to report the presence or absence of metallo beta-lactamase (MBL) enzymes based on inhibitory concentrations of imipenem and imipenem+EDTA. This term was created for, but is not limited in use to, bioMerieux's ETEST MBL assay.

Part Descriptions

LP232455-8   Metallo beta-lactamase by imipenem to imipenem+EDTA inhibitory concentration ratio
Metallo beta-lactamase (MBL) enzymes are resistance enzymes whose activity is dependent on divalent cations such as zinc or cadmium, so that they can be inhibited by metal chelators such as EDTA. The presence of MBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as imipenem or meropenem, with the IC of that antimicrobial plus EDTA. Source: Regenstrief LOINC

LP234471-3   Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Metallo beta-lactamase by imipenem to imipenem+EDTA inhibitory concentration ratio
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Gradient strip ARD

Additional Names

Long Common Name
MBL by imipenem to imipenem-EDTA IC ratio [Presence] by ARD gradient strip
Short Name
MBL imi + imi-EDTA IC rto Islt Ql Grad
Display Name
MBL by imipenem to imipenem-EDTA IC ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha Get Info
MBL by Imipenem to Imipenem-EDTA IC Ratio

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Αναλογία ανασταλτικής συγκέντρωσης μεταλλο-β-λακταμάσης από ιμιπενέμη προς ιμιπενέμη+αιθυλενοδιαμινοτετραοξικό οξύ:PrThr:Pt:Απομονωμένο στέλεχος:Ord:Λωρίδα με διαβαθμίσεις ARD
Synonyms: PrThr Αναλογία ανασταλτικής συγκέντρωσης μεταλλο-β-λακταμάσης από ιμιπενέμη προς ιμιπενέμη+αιθυλενοδιαμινοτετραοξικό οξύ Ιμιπενέμη Ιμιπενέμη+Αιθυλενοδιαμινοτετραοξικό οξύ
es-ES Spanish (Spain) ESBL para la concentración inhibitoria de imipenem frente a la de imipenem-EDTA:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.
es-MX Spanish (Mexico) Relación de concentración inhibidora de metalo betalactamasa por imipenem a imipenem + EDTA:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
fr-FR French (France) Ratio CMI métallo bêta lactamase imipénème/EDTA:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-IT Italian (Italy) Rapporto concentrazione inibitoria metallo beta-lattamasi mediante imipenem/imipenem+EDTA:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD
Synonyms: Gradiente striscia (E-test) Presenza o Soglia Punto nel tempo (episodio) Rapporto IC MBL mediante imipenem/imipenem+EDTA Striscia di gradiente per detezione resistenza ant Suscettibilità agli antibiotici
zh-CN Chinese (China) 亚胺培南相对于亚胺培南+EDTA抑菌浓度比值法金属 beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法
Synonyms: ARD 梯度胶条法;E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条;ARD;antimicrobial resistance detection B Betalactamase Beta-内酰胺酶 B-Lactamase B-内酰胺酶 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 β β内酰胺酶 β-内酰胺酶 亚胺培南+EDTA（乙二胺四乙酸、依地酸、乙二胺四醋酸法） 亚胺培南相对于（与、相对）亚胺培南+EDTA（乙二胺四乙酸、依地酸、乙二胺四醋酸法）抑菌浓度（抑制浓度、IC）比值（比例、比、比率）法金属 beta 内酰胺酶（金属β内酰胺酶、金属β-内酰胺酶、MBL）;亚胺培南相对于亚胺培南+EDTA抑菌浓度比值法 MBL 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 贝塔

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