85337-4

Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain

Active

Part Description

LP18567-5 Estrogen receptor
Estrogen receptor refers to a group of receptors which are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding.

Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive", and can be demonstrated in such tissues using immunohistochemistry. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Estrogen receptor

LOINC Names Get Info

Fully-Specified Name: Estrogen receptor Ag:PrThr:Pt:Breast cancer specimen:Ord:Immune stain
Long Common Name: Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain
Short Name: ER Ag Br ca spec Ql ImStn
Display Name: Estrogen receptor Ag Immune stain Ql (Breast cancer specimen)
Consumer Name Alpha Get Info: Estrogen receptor antigen, Breast cancer specimen

Part Model Get Info

Component
Estrogen receptor Ag
LP38115-9
- Analyte
  Estrogen receptor Ag
  LP38115-9
  - Component Numerator
    Estrogen receptor Ag
    LP38115-9
    - Component Numerator Core
      Estrogen receptor
      LP18567-5
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Breast cancer specimen
LP247851-1
- System Core
  Breast cancer specimen
  LP247851-1
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Immune stain
LP6333-1

Preferred Answer List: LL2038-9

Source: Quest Diagnostics Inc.

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)			LA11884-6

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
85904-1	Cancer pathology panel - Breast cancer specimen by CAP cancer protocols

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Estrogenový receptor Ag:Přítomnost nebo práh:Časový bod:Vzorek karcinomu prsu:Ordinální:Imunobarvení
el-GR	Greek (Greece)	Υποδοχέας οιστρογόνων Αντιγόνο:PrThr:Pt:Δείγμα καρκίνου του μαστού:Ord:Ανοσολογική χρώση Synonyms: Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Δείγμα Δείγμα καρκίνου Δείγμα καρκίνου του μαστού Καρκίνος Μαστός Οιστρογόνα Υποδοχέας οιστρογόνων
es-ES	Spanish (Spain)	Receptor de estrógeno Antígeno:PrThr:Punto temporal:Muestra de cancer de mama:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	Receptor de estrógeno Ag:Presencia o umbral:Punto temporal:Muestra de cáncer de mama:Ordinal:Mancha inmune
fr-FR	French (France)	Estrogènes récepteurs Ag:Présence/Seuil:Ponctuel:Tissu mammaire cancereux:Qualitatif:Coloration immune
it-IT	Italian (Italy)	Estrogeno, recettore, Ag:PrThr:Pt:Tumore della mammella, campione:Ord:Colorazione immunologica Synonyms: Campione di tumore Campione di tumore della mammella Neoplasia maligna Patologia Petto Presenza o Soglia Punto nel tempo (episodio) Recettore degli estrogeni
pl-PL	Polish (Poland)	Receptor estrogenowy Ag:granica wykrywalności:punkt w czasie:próbka nowotwór piersi:uporządkowany:barwienie immunohistochemiczne Synonyms: Antygen receptora estrogenowego ER nowotwór pierś
zh-CN	Chinese (China)	雌激素受体抗原:存在情况或阈值:时间点:乳腺癌标本:序数型:免疫染色法 Synonyms: Ag ER;ERA;雌激素受体（Estrogen Receptor，ER） EST;Estr;女性激素;女性激素类;女性激素类内分泌化学成分;女性荷尔蒙;女性荷尔蒙类;女性荷尔蒙类内分泌化学成分;雌性激素;雌性激素类;雌性激素类内分泌化学成分;雌性荷尔蒙;雌性荷尔蒙类;雌性荷尔蒙类内分泌化学成分;雌激素类;雌激素类内分泌化学成分;雌酮+雌二醇;雌酮+雌二醇+雌三醇乳房乳腺癌（乳癌）标本（样本、样品、试样）供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间染法染色方法染色法样品样本癌癌（癌症、癌变）标本（样本、样品、试样）着色着色方法着色法试样雌激素受体 Ag

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.