85583-3

Chikungunya virus RNA [Presence] in Plasma from Donor by NAA with probe detection

Active

Term Description

This term is used for assays that detect Chikungunya virus RNA in donor plasma. This term was created for, but is not limited in use to, the submitter's cobas CHIKV assay.

Part Descriptions

LP21132-3 Chikungunya virus
A species of ALPHAVIRUS causing an acute dengue-like fever. Source: National Library of Medicine, MeSH 2006

LP21132-3 Chikungunya virus
Chikungunya virus (CHIKV) belongs to the mosquito-borne alphavirus genus, in the family Togaviridae, and was first observed in epidemic form in Africa. Serologically, CHIKV belongs to the Semliki Forest (SF) subgroup of alphaviruses. Infection in humans is characterized by rash, high fever and, its hallmark feature, severe arthritis that can persist for years. CHIKV is a small, spherical, enveloped, positive-strand RNA virus. The virion consists of an envelope and a nucleocapsid. The envelope glycoproteins of alphaviruses are the distinguishing factors for testing. The CHIKV genome encodes for two polyproteins; the non-structural polyprotein consisting of four proteins (nsP1, nsP2, nsP3 and nsP4) and the structural polyprotein consisting of five proteins (Capsid, E3, E2, 6K and E1). CHIKV has spikes on the virion surface that are each formed by three E1-E2 heterodimers, where the E1 glycoproteins mediate fusion and E2 glycoproteins interact with the host receptor. PMID: 20111039
CHIKV can be detected between the first and fourth day of infection (the acute phase) using PCR or virus cultivation, and virus-specific IgM and IgG antibodies can be detected during the 8th to the 10th day of infection. Antibody investigation should be performed using serum samples from the acute and convalescent stage. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Chikungunya virus RNA:PrThr:Pt:Plas^Donor:Ord:Probe.amp.tar
Long Common Name: Chikungunya virus RNA [Presence] in Plasma from Donor by NAA with probe detection
Short Name: CHIKV RNA Plas Donr Ql NAA+probe
Display Name: CHIKV RNA NAA+probe Ql (P donor)
Consumer Name Alpha Get Info: Chikungunya virus, Donor Blood

Part Model Get Info

Component
Chikungunya virus RNA
LP66615-3
- Analyte
  Chikungunya virus RNA
  LP66615-3
  - Component Numerator
    Chikungunya virus RNA
    LP66615-3
    - Component Numerator Core
      Chikungunya virus
      LP21132-3
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas^Donor
LP186026-3
- System Core
  Plas
  LP7479-1
- Super System
  Donor
  LP7742-2
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL2888-7

Source: Roche Diagnostics International

Answer	Code	Score	Answer ID
NonreactiveCopyright http://snomed.info/sct ID:131194007 Non-reactive (qualifier value)			LA15256-3
ReactiveCopyright http://snomed.info/sct ID:11214006 Reactive (qualifier value)			LA15255-5
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value)			LA15841-2

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.63 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus Chikungunya RNA:Přítomnost nebo práh:Časový bod:Plazma^Dárce:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Chikungunya-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Plasma^Donor:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ιός Chikungunya RNA:PrThr:Pt:Πλάσμα^Δότης:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: MICRO Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Δότης Ιός Ιός Chikungunya Πλάσμα
es-ES	Spanish (Spain)	Virus Chikungunya RNA:PrThr:Punto temporal:Plasma^donante:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus Chikungunya:Presencia o umbral:Punto temporal:Plasma ^ Donante:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Virus Chikungunya ARN:Présence-Seuil:Temps ponctuel:Plasma^Donneur:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Chikungunya virus ARN:Présence/Seuil:Ponctuel:Plasma^donneur:Qualitatif:PCR amplification de cible
fr-BE	French (Belgium)	Virus Chikungunya ARN:PrThr:Temps ponctuel:Plasma^Donneur:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	Chikungunya virus RNA:PrThr:Pt:Plasma^donatore:Ord:Sonda.amp.tar Synonyms: CHIK Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Chikungunya-virus RNA:aanwezigheid:moment:plasma^donor:ordinaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus Chikungunya RNA:granica wykrywalności:punkt w czasie:osocze^dawca:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa Chikungunya Wirus Chikungunya
ru-RU	Russian (Russian Federation)	Чикунгунья вирус РНК:PrThr:ТчкВрм:Плаз^донор:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Плазма Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Chikungunya virus RNA:MevcEşik:Zmlı:Plaz^verici:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	基孔肯亚病毒 RNA:存在情况或阈值:时间点:血浆^供体:序数型:探针法.基因扩增.靶向 Synonyms: 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向奇昆古尼亚病毒;基孔肯雅病毒;CHIKV 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.