LOINC
Version 2.67

85621-1Zika virus RNA [Presence] in Amniotic fluid by NAA with probe detectionActive

Term Description

This term is used to report the presence of Zika virus RNA in amniotic fluid. For assays that target the Zika virus envelope (E) gene, use [LOINC: 81149-7]. This term was created for , but is not limited in use to, the Altona RealStar Zika virus PCR assay.
Source: Regenstrief LOINC

Part Descriptions

LP200137-0   Zika virus
Zika virus (ZIKV) is a flavivirus transmitted primarily by the Aedes mosquito which was first identified in a sentinel monkey in the Zika forest in Uganda in 1947. Since 2014 it has spread explosively in the Americas where it has infected hundreds of thousands of people. About 80% of those infected are asymptomatic. Common symptoms include fever, headache, rash, arthralgia and conjunctivitis. Since the end of 2015, there has been an increase in ZIKV-associated cases of Guillain-Barre syndrome and a tremendous increase in cases of microcephaly in fetuses and newborns in Brazil, raising worldwide public health concern. Recent predictions are that the mosquito species A. Albopictus, which can hibernate and survive cool temperatures, will carry ZIKV to more temperate areas of North America, Australia and Southern Europe. It is still not clear whether ZIKV in humans increases viral titers enough to trigger a new cycle when an infected person is bitten by a naïve mosquito. Direct human-to-human transmission has been documented to occur perinatally, sexually (primarily through semen), through breastfeeding, blood transfusion and through occupational transmission in the laboratory setting. There are currently no specific anti-viral agents, vaccination or medical prophylaxis available. [PMID: 27148186] Source: Regenstrief LOINC

LP203271-4   Zika virus RNA
Zika virus contains an inner nucleocapsid composed of RNA and multiple copies of the viral capsid (C) protein. The outer host contains 180 copies each of two proteins: the viral membrane (M) protein and the envelope (E) protein (Kostyuchenko et al., 2016; Sirohi et al., 2016). Viral RNA of the Zika virus has been identified in the brain and liver of fetuses and in the brain, eyes, spleen, liver and placenta of pregnant mothers, with the highest viral load existing in the placenta.(Adams Waldorf et al., 2016). Source: Regenstrief LOINC

Fully-Specified Name

Component
Zika virus RNA
Property
PrThr
Time
Pt
System
Amnio fld
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
ZIKV RNA Amn Ql NAA+probe
Display Name
ZIKV RNA NAA+probe Ql (Amn fld)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.63
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG32774-8 Zika virus

Language Variants Get Info

zh-CNChinese (CHINA)
寨卡病毒 RNA:存在情况或阈值:时间点:羊水:序数型:探针法.基因扩增.靶向
nl-NLDutch (NETHERLANDS)
zikavirus RNA:aanwezigheid:moment:vruchtwater:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (FRANCE)
Zika virus ARN:Présence/Seuil:Ponctuel:Liquide amniotique:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Zika virus , RNA:PrThr:Pt:Liquido amniotico:Ord:Sonda.amp.tar
es-ESSpanish (SPAIN)
Virus Zika RNA:PrThr:Punto temporal:Fluido Ammiótico:Ord:Sonda con amplificación dirigida
tr-TRTurkish (TURKEY)
Zika virüs RNA:MevcEşik:Zmlı:Amniyon sv:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85621-1