85831-6

Beta-lactam resistance ESBL blaBEL gene [Presence] by Molecular method

Active

Term Description

This test reports the presence of the BEL extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.

Part Description

LP248299-2 Bacterial beta-lactam resistance ESBL blaBEL gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. PMID: 19246801 -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial beta-lactam resistance ESBL blaBEL gene:PrThr:Pt:Isolate/Specimen:Ord:Molgen
Long Common Name: Beta-lactam resistance ESBL blaBEL gene [Presence] by Molecular method
Short Name: ESBL blaBEL gene Islt/Spm Ql
Display Name: Beta-lactam resistance ESBL blaBEL gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Beta-lactam Resistance ESBL blaBEL gene

Part Model Get Info

Component
Bacterial beta-lactam resistance ESBL blaBEL gene
LP248299-2
- Analyte
  Bacterial beta-lactam resistance ESBL blaBEL gene
  LP248299-2
  - Component Numerator
    Bacterial beta-lactam resistance ESBL blaBEL gene
    LP248299-2
    - Component Numerator Core
      Bacterial beta-lactam resistance ESBL blaBEL gene
      LP248299-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate/Specimen
LP266970-5
- System Core
  Isolate/Specimen
  LP266970-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.67 (MIN)
Change Reason: Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
93698-9	Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen blaBEL bakteriální rezistence na beta-laktamy ESBL:Přítomnost nebo práh:Časový bod:Izolát/vzorek:Ordinální:Molekulární genetika
de-DE	German (Germany)	Bakterielle Beta-Lactam-Resistenz ESBL blaBEL-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch Synonyms: Extended Spectrum beta-lactamases
el-GR	Greek (Greece)	Βακτηριακή ανθεκτικότητα στη β-λακτάμη γονίδιο ESBL blaBEL:PrThr:Pt:Απομονωθέν στέλεχος/Δείγμα:Ord:Μοριακή γενετική Synonyms: ABXBACT Ord PrThr Pt Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Βακτηριακή ανθεκτικότητα στη β-λακτάμη γονίδιο ESBL blaBEL Γονίδιο Δείγμα Μοριακή γενετική
es-ES	Spanish (Spain)	gen bacteriano ESBL blaBEL resistente a beta-lactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Resistencia bacteriana a betalactámicos BLEE gen blaBEL:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR	French (France)	Résistance bactérienne aux bêta-lactamines gène ESBL blaBEL:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Resistenza batterica beta-lactamica, gene ESBL blaBEL:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Gene ESBL blaBEL di resistenza batterica beta-lactamica Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële bètalactamresistentie ESBL blaBEL-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: bacterieel beta-lactam resistentie ESBL blaBEL gen isolaat/specimen molgen
pl-PL	Polish (Poland)	Bakteryjna oporność na beta-laktamy ESBL blaBEL gen:granica wykrywalności:punkt w czasie:szczep/izolat lub próbka:uporządkowany:genetyka molekularna Synonyms: diagnostyka molekularna Gen blaBEL bakteryjnej oporności na beta-laktamy ESBL
zh-CN	Chinese (China)	细菌 beta-内酰胺耐药 ESBL blaBEL 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: B β 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本电阻细菌 beta-内酰胺（β-内酰胺）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） ESBL（超广谱β-内酰胺酶） blaBEL 基因细菌性细菌的耐性试样贝塔遗传基因;遗传因子;吉恩;生物基因阻力

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.