86199-7
Rotavirus A Ag [Presence] in Tissue by Immune stain
Active
Part Description
LP204843-9 Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. PMID: 2556635[http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub] PMID: 27462899
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rotavirus A Ag
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Immune stain
Additional Names
- Short Name
- RVA Ag Tiss Ql ImStn
- Display Name
- Rotavirus A Ag Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- Rotavirus A antigen, Tissue
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.64
- Change Reason
- Updated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.; Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Rotavirus A Ag: |
es-ES | Spanish (Spain) | Rotavirus A Antígeno: |
es-MX | Spanish (Mexico) | Rotavirus A Ag: |
fr-FR | French (France) | Rotavirus A Ag: |
it-IT | Italian (Italy) | Rotavirus A, Ag: Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & |
nl-NL | Dutch (Netherlands) | Rotavirus A Ag: Synonyms: antigeen |
pl-PL | Polish (Poland) | Rotawirus grupy A Ag: Synonyms: Antygen Rotawirusa A barwnik immunologiczny |
zh-CN | Chinese (China) | 轮状病毒 A 组 抗原: Synonyms: A 型 A 型抗原 Ag ROTAV; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=86199-7
Third Party Copyright
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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright