Version 2.78

Part Description

LP204843-9   Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. PMID: 2556635[http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub] PMID: 27462899 Source: Regenstrief LOINC

Fully-Specified Name

Component
Rotavirus A Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
RVA Ag Tiss Ql ImStn
Display Name
Rotavirus A Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info
Rotavirus A antigen, Tissue

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.64
Change Reason
Updated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.; Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Rotavirus A Ag:Nachweis oder Schwellenwert:Zeitpunkt:Gewebe:Ordinal:Immunfärbung
es-ES Spanish (Spain) Rotavirus A Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX Spanish (Mexico) Rotavirus A Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
fr-FR French (France) Rotavirus A Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-IT Italian (Italy) Rotavirus A, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL Dutch (Netherlands) Rotavirus A Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
Synonyms: antigeen
pl-PL Polish (Poland) Rotawirus grupy A Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:półilościowy:barwnik immunologiczny
Synonyms: Antygen Rotawirusa A barwnik immunologiczny
zh-CN Chinese (China) 轮状病毒 A 组 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
Synonyms: A 型 A 型抗原 Ag ROTAV;RV 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 着色 着色方法 着色法 轮状病毒(ROTAV、RV) A 组;A 组轮状病毒

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86199-7