86609-5
Noroxymorphone/Creatinine [Mass Ratio] in Urine by Confirmatory method
Active
Part Descriptions
LP248581-3 Noroxymorphone
Oxycodone is in the opioid drug class and is a potent pain reliever. Noroxymorphone is a major secondary metabolite of oxycodone. It is formed after O-demethylation of noroxycodone by CYP2D6 and to a lesser extent by N-demethylation of oxymorphone by Cyp3A4 and 2D6. Noroxymorphone has minimal analgesic effect when oxycodone is administered orally or systemically. Noroxymorphone is a powerful agonist to the mu-opioid receptor when oxycodone is administered intrathecally suggesting that noroxymorphone does not readily cross the blood-brain barrier. ( PMID: 18227301) (http://www-3.unipv.it/balto98/Lezioni%20IUSS/noroxymorphone.pdf)
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Noroxymorphone/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- Noroxymorphone/Creat Ur Cfm
- Display Name
- Noroxymorphone/Creatinine Confirm (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Noroxymorphone/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4992
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Noroximorfona/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Noroximorfona / Creatinina: |
| fr-FR | French (France) | Noroxymorphone/créatinine: |
| it-IT | Italian (Italy) | Norossimorfone/Creatinina: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
| nl-NL | Dutch (Netherlands) | noroxymorfon/creatinine: Synonyms: kreatinine |
| zh-CN | Chinese (China) | 去甲基羟吗啡酮/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| ng/mg{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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LOINC Copyright
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