86696-2

Rotavirus B RNA [Nucleotide sequence] in Isolate by Sequencing

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Part Descriptions

LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP248423-8 Rotavirus B
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus B (RVB) infect both humans and animals, and were the cause of severe diarrheal epidemics in China between 1982 and 1987. RVB has been isolated in lambs, pigs, cattle, goats and rats. India, Bangladesh, and Myanmar have also experienced acute outbreaks of gastroenteritis caused by infection with RVB. PMID: 2556635 http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub PMID: 21985827 PMID: 24155654 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Rotavirus B RNA:Seq:Pt:Isolate:Nom:Sequencing
Long Common Name: Rotavirus B RNA [Nucleotide sequence] in Isolate by Sequencing
Short Name: RVB RNA Islt-Seq
Display Name: Rotavirus B RNA sequence Nom (Isol)
Consumer Name Alpha Get Info: Rotavirus B

Part Model Get Info

Component
Rotavirus B RNA
LP286991-7
- Analyte
  Rotavirus B RNA
  LP286991-7
  - Component Numerator
    Rotavirus B RNA
    LP286991-7
    - Component Numerator Core
      Rotavirus B
      LP248423-8
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Seq
LP62164-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Nom
LP7750-5
Method
Sequencing
LP150045-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.61 (ADD)
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Rotavirus B RNA:Nukleotidová sekvence:Časový bod:Izolát:Nominální:Sekvenace
de-DE	German (Germany)	Rotavirus B RNA:Sequenz:Zeitpunkt:Isolat:Nominal:Sequenzierung
el-GR	Greek (Greece)	Ροταϊός B RNA:Seq:Pt:Απομονωμένο στέλεχος:Nom:Αλληλούχιση Synonyms: B MICRO Nom Pt RNA Seq Αλληλούχιση Απομονωμένο στέλεχος Ροταϊός Ροταϊός B
es-ES	Spanish (Spain)	Rotavirus B RNA:Secuencia de nucleótidos:Punto temporal:Aislado:Nom:Secuenciación
es-MX	Spanish (Mexico)	ARN del rotavirus B:Secuencia de nucleótidos:Punto temporal:Aislado:Nominal:Secuenciación
fr-FR	French (France)	Rotavirus B ARN:Séquence nucléotidique:Ponctuel:Isolat:Résultat nominal:Séquençage
it-IT	Italian (Italy)	Rotavirus B RNA:Seq:Pt:Isolato:Nom:Sequenziamento Synonyms: Microbiologia Punto nel tempo (episodio) Sequenza nucleotidica
nl-NL	Dutch (Netherlands)	Rotavirus B RNA:nucleotidevolgorde:moment:isolaat:nominaal:sequencing
pl-PL	Polish (Poland)	Rotawirus B RNA:sekwencja nukleotydów:punkt w czasie:izolat:skala nominalna:sekwencjonowanie Synonyms: RNA Rotawirusa B wynik kategorialny
zh-CN	Chinese (China)	轮状病毒 B RNA:序列:时间点:分离株:名义型:序列测定 Synonyms: B 型 ROTAV;RV 分离物;分离菌;分离菌株;隔离种群分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答序列分析;测序微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 核苷酸序列轮状病毒（ROTAV、RV） B 组;B 组轮状病毒

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.