86701-0

Rotavirus A RNA [Cycle Threshold #] in Specimen by NAA with probe detection

Active

Term Description

Sample types for this test include porcine feces and fecal swabs, intestinal tissue and environmental swabs.

Part Description

LP204843-9 Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. PMID: 2556635 http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub PMID: 27462899 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Rotavirus A RNA:ThreshNum:Pt:XXX:Qn:Probe.amp.tar
Long Common Name: Rotavirus A RNA [Cycle Threshold #] in Specimen by NAA with probe detection
Short Name: RVA RNA Ct Spec Qn NAA+probe
Display Name: Rotavirus A RNA NAA+probe (Specimen) [ThreshNum]
Consumer Name Alpha Get Info: Rotavirus A, Specimen

Part Model Get Info

Component
Rotavirus A RNA
LP220378-6
- Analyte
  Rotavirus A RNA
  LP220378-6
  - Component Numerator
    Rotavirus A RNA
    LP220378-6
    - Component Numerator Core
      Rotavirus A
      LP204843-9
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ThreshNum
LP188772-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe.amp.tar
LP6464-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.61
Last Updated: Version 2.69 (MIN)
Change Reason: Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Rotavirus A RNA:Prahová hodnota:Časový bod:XXX:Kvantitativní:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Rotavirus A RNA:Ct-Wert:Zeitpunkt:XXX:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ροταϊός Α RNA:ThreshNum:Pt:XXX:Qn:Ανιχνευτής.ενίσχυση.στόχου Synonyms: A MICRO Pt Qn RNA ThreshNum XXX Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ροταϊός Ροταϊός Α
es-ES	Spanish (Spain)	Rotavirus A RNA:ThreshNnum:Punto temporal:XXX:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	ARN del rotavirus A:ThreshNum:Punto temporal:XXX:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Rotavirus A ARN:Cycle seuil:Ponctuel:Milieux divers:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	Rotavirus A RNA:Thresnum:Pt:XXX:Qn:Sonda.amp.tar Synonyms: Limite di soglia Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Rotavirus A RNA:drempelwaarde nummer:moment:XXX:kwantitatief:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Rotawirus grupy A RNA:wartość progowa:punkt w czasie:XXX:ilościowy:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA Rotawirusa A
zh-CN	Chinese (China)	轮状病毒 A 组 RNA:阈值循环圈数:时间点:XXX:定量型:探针法.基因扩增.靶向 Synonyms: A 型 ROTAV;RV 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值经过扩增的脱氧核糖核酸探针轮状病毒（ROTAV、RV） A 组;A 组轮状病毒

Example Units

Unit	Source
{Ct_value}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.