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Term Description

Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein is the major envelope type I glycoprotein of the virion and contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Porcine epidemic diarrhea virus whole genome:Seq:Pt:Isolate:Nom:Sequencing
Long Common Name
Porcine epidemic diarrhea virus whole genome [Nucleotide sequence] in Isolate by Sequencing
Short Name
PEDV whole genome Islt-Seq
Display Name
Porcine epidemic diarrhea virus whole genome sequence Nom (Isol)
Consumer Name Alpha Get Info
Porcine Epidemic Diarrhea virus Whole Genome

Part Model Get Info

  • Component
    Porcine epidemic diarrhea virus whole genome
    LP249877-4
    • Analyte
      Porcine epidemic diarrhea virus whole genome
      LP249877-4
      • Component Numerator
        Porcine epidemic diarrhea virus whole genome
        LP249877-4
        • Component Numerator Core
          Porcine epidemic diarrhea virus whole genome
          LP249877-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Seq
    LP62164-6
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Sequencing
    LP150045-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus epidemické prasečí průjmové nemoci (PED) celý genom:Nukleotidová sekvence:Časový bod:Izolát:Nominální:Sekvenace
el-GRGreek (Greece)Ολόκληρο γονιδίωμα ιού επιδημικής διάρροιας των χοίρων:Seq:Pt:Απομονωμένο στέλεχος:Nom:Αλληλούχιση
Synonyms: MICRO Nom Pt Seq Αλληλούχιση Απομονωμένο στέλεχος Ιός Ιός επιδημικής διάρροιας των χοίρων Ολόκληρο γονιδίωμα ιού επιδημικής διάρροιας των χοίρων Των χοίρων
es-ESSpanish (Spain)Genoma completo virus diarrea epidémica porcina:Secuencia de nucleótidos:Punto temporal:Aislado:Nom:Secuenciación
es-MXSpanish (Mexico)Genoma completo del virus de la diarrea epidémica porcina:Secuencia de nucleótidos:Punto temporal:Aislado:Nominal:Secuenciación
it-ITItalian (Italy)Virus della diarrea epidemica suina, intero genoma:Seq:Pt:Isolato:Nom:Sequenziamento
Synonyms: Intero genoma di virus PED Microbiologia Punto nel tempo (episodio) Sequenza nucleotidica Virus PED
nl-NLDutch (Netherlands)'porcine' epizoötisch diarreevirus geheel genoom:nucleotidevolgorde:moment:isolaat:nominaal:sequencing
Synonyms: epizoötisch diarreevirus van varken porcine
pl-PLPolish (Poland)Wirus epidemicznej biegunki świń cały genom:sekwencja nukleotydów:punkt w czasie:izolat:skala nominalna:sekwencjonowanie
Synonyms: wynik kategorialny
zh-CNChinese (China)猪流行性腹泻病毒全基因组:序列:时间点:分离株:名义型:序列测定
Synonyms: PEDV 全（完整、全部）基因组 下痢;泄泻;下利;泻肚 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 核苷酸序列 猪传染性腹泻病毒;PEDv 猪的 猪科 猪科的

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86928-9