87330-7
Porcine circovirus type 2 neutralizing antibody [Titer] in Serum by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP249707-3 Porcine circovirus type 2
Veterinary Medicine:
Porcine circoviruses (PCV) are small nonenveloped DNA viruses in the Circoviridae family that contain a single-stranded circular genome. PCV are the smallest viruses replicating autonomously in eukaryotic cells by utilizing the host polymerase for genome amplification. Two types of PCV have been characterised, PCV1 and PCV2. PCV1 is nonpathogenic in adult pigs, while PCV2 is a major pathogen. PMID: 21945213. The primary effect of PCV2 is postweaning multisystemic wasting syndrome (PMWS). Pigs with PMWS have weakness, difficulty breathing, enlarged lymphnodes, diarrhea, and yellowing of the skin. Lesions associated with the presence of PCV2 have been found in the lymphatic system, the lungs, liver, kidney, heart, gastrointestinal tract and pancreas. Co-infection of PCV with porcine parvovirus or porcine reproductive and respiratory syndrome (PRRS) virus enhances PMWS. PMID: 10690769Infection of porcine circovirus in humans is non-productive.[cordis.europa.eu/result/rcn/33358_en.html]
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Porcine Circovirus type 2 Ab.Neut:
Titr: Pt: Ser: SemiQn: Neut - Long Common Name
- Porcine circovirus type 2 neutralizing antibody [Titer] in Serum by Neutralization test
- Short Name
- PCV2 NAb Titr Ser Nt
- Display Name
- PCV type 2 neut ab Neut test (S) [Titer]
- Consumer Name Alpha Get Info
- PCV type 2 neutralizing antibody, Blood
Part Model Get Info
- Component
- Porcine circovirus type 2 Ab.Neut
LP249703-2
- Analyte
- Porcine circovirus type 2 Ab.Neut
LP249703-2
- Component Numerator
- Porcine circovirus type 2 Ab.Neut
LP249703-2
- Component Numerator Core
- Porcine circovirus type 2
LP249707-3
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Titr
LP6881-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- SemiQn
LP436123-6
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.75 (MAJ)
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Prasečí cirkovirus typ 2 Ab neutralizační: |
| el-GR | Greek (Greece) | Κυκλοϊός των χοίρων τύπου 2 Ab.Neut: Synonyms: Ab.Neut MICRO Pt Titr Type Αντίσωμα Ημιποσοτική Κυκλοϊός των χοίρων Κυκλοϊός των χοίρων τύπου 2 Ορός Ουδετερόφιλα Των χοίρων |
| es-ES | Spanish (Spain) | Circovirus porcino tipo 2 Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Circovirus porcino tipo 2 Ab.Neut: |
| it-IT | Italian (Italy) | Circovirus suino tipo 2 Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo |
| nl-NL | Dutch (Netherlands) | varkenscircovirus type 2 As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Cirkowirus świń typu 2 Ab.Neutralizujące: Synonyms: Przeciwciała neutralizujące IgG do Cirkowirusa świń typu 2 |
| zh-CN | Chinese (China) | 猪圆环病毒 2 型 抗体.中和: Synonyms: Ⅱ Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://