87376-0
Escherichia coli Stx1 toxin stx1 gene [Presence] in Isolate by NAA with probe detection
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Part Description
LP262487-4 Escherichia coli Stx1 toxin stx1 gene
The Stx1 toxin A subunit is encoded by the stx1 gene [www.uniprot.org/uniprot/ ?query=stx1+escherichia+coli&sort=score] and the Stx2 toxin A subunit is encoded by the stx2 gene.[UniProt: K0JD26] Stx1a and Stx2a are produced by some serogroups of Escherichia coli (also known as Vero toxins and previously referred to as Shiga-like toxins) are two cytotoxins that cause hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The two toxins produce similar symptoms, but are immunologically unique. Both toxins are composed of a single copy of subunit A and five copies of subunit B. Stx1a and Stx1b induce host cell apoptosis by removing an adenine residue from the 28S rRNA of the 60S ribosome, with RNA-N-glycosidase activity provided by subunit A. The five B subunits bind to the host cell receptor present on endothelial cells. PMID: 25530917 Shigella toxin-producing Escherichia coli (STEC) has become a serious food-borne pathogen. Outbreaks of STEC have been associated with the consumption of pork products resulting in HC and HUS. STEC in swine has been demonstrated to cause edema disease. Epidemiological studies throughout the world have proven that STEC can be harbored and shed by domestic swine. PMID: 24397985
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Escherichia coli Stx1 toxin stx1 gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- EC stx1 gene Islt Ql NAA+probe
- Display Name
- E. coli stx1 gene NAA+probe Ql (Isol)
- Consumer Name Alpha Get Info
- Escherichia coli stx1 toxin stx1 gene
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.64
- Change Reason
- Updated Component from "Escherichia coli stx1 gene" based on the current E. coli nomenclature and LOINC model
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Escherichia coli Stx1 Toxin stx1-Gen: |
es-ES | Spanish (Spain) | Gen stx1 Escherichia coli: |
es-MX | Spanish (Mexico) | Escherichia coli Toxina Stx1 Gen stx1: |
fr-FR | French (France) | Escherichia coli toxine stx1 gène: |
it-IT | Italian (Italy) | Escherichia coli tossina Stx1, gene stx1: Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
nl-NL | Dutch (Netherlands) | Escherichia coli Stx1-toxine stx1-gen: Synonyms: probe.amp.tar |
zh-CN | Chinese (China) | 大肠埃希菌 Stx1 毒素 stx1 基因: Synonyms: E coli; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=87376-0
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright