Version 2.78

Part Description

LP262477-5   Escherichia coli Stx2 toxin stx2 gene
The Stx1 toxin A subunit is encoded by the stx1 gene [www.uniprot.org/uniprot/ ?query=stx1+escherichia+coli&sort=score] and the Stx2 toxin A subunit is encoded by the stx2 gene.[UniProt: K0JD26] Stx1a and Stx2a are produced by some serogroups of Escherichia coli (also known as Vero toxins and previously referred to as Shiga-like toxins) are two cytotoxins that cause hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The two toxins produce similar symptoms, but are immunologically unique. Both toxins are composed of a single copy of subunit A and five copies of subunit B. Stx1a and Stx1b induce host cell apoptosis by removing an adenine residue from the 28S rRNA of the 60S ribosome, with RNA-N-glycosidase activity provided by subunit A. The five B subunits bind to the host cell receptor present on endothelial cells. PMID: 25530917 Shigella toxin-producing Escherichia coli (STEC) has become a serious food-borne pathogen. Outbreaks of STEC have been associated with the consumption of pork products resulting in HC and HUS. STEC in swine has been demonstrated to cause edema disease. Epidemiological studies throughout the world have proven that STEC can be harbored and shed by domestic swine. PMID: 24397985 Source: Regenstrief LOINC

Fully-Specified Name

Component
Escherichia coli Stx2 toxin stx2 gene
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Probe.amp.tar

Additional Names

Long Common Name
Escherichia coli Stx2 toxin stx2 gene [Presence] in Isolate by NAA with probe detection
Short Name
EC stx2 gene Islt Ql NAA+probe
Display Name
E. coli stx2 gene NAA+probe Ql (Isol)
Consumer Name Alpha Get Info
Escherichia coli stx2 toxin stx2 gene

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.64
Change Reason
Updated Component from "Escherichia coli stx2 gene" based on the current E. coli nomenclature and LOINC model
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
88116-9 Escherichia coli gene panel - Specimen by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Escherichia coli Stx2 Toxin stx2-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Gen stx2 Escherichia coli:PrThr:Punto temporal:Aislado:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Escherichia coli Toxina Stx2 Gen stx2:Presencia o umbral:Punto temporal:Aislado:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Escherichia coli toxine stx2 gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Escherichia coli tossina Stx2, gene stx2:PrThr:Pt:Isolato:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Escherichia coli Stx2-toxine stx2-gen:aanwezigheid:moment:isolaat:ordinaal:probe-detectie
Synonyms: probe.amp.tar
zh-CN Chinese (China) 大肠埃希菌 Stx2 毒素 stx2 基因:存在情况或阈值:时间点:分离株:序数型:探针法.基因扩增.靶向
Synonyms: E coli;大肠埃希氏杆菌;大肠埃希氏菌;大肠杆菌 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分离物;分离菌;分离菌株;隔离种群 大肠埃希菌（E coli、大肠埃希氏杆菌、大肠埃希氏菌、大肠杆菌） Stx2 毒素 stx2 基因;大肠埃希菌 stx2 基因 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 经过扩增的 脱氧核糖核酸探针 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87377-8