87417-2
Cytolethal distending toxin B and Vinculin Ab panel - Serum by Immunoassay
Active
87418-0 Cytolethal distending toxin B Ab [Units/volume] in Serum by Immunoassay
Part Descriptions
LP262441-1 Cytolethal distending toxin B
Cytolethal distending toxin B (CdtB) is a protein that is produced by gram negative bacteria. CdtB targets eukaryotic DNA. PMID: 16427513 Antibodies against this toxin can cross react with vinculin, a cytoskeletal protein found in epithelial cells. In animal models, these vinculin antibodies have been shown to cause symtoms similar to irritable bowel syndrome (IBS). CdtB antibodies are useful as biomarkers for irritable bowel syndrome with diarrhea (D-IBS) in humans, and may help distinguish D-IBS from inflammatory bowel disease in the workup of chronic diarrhea. PMID: 25970536
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytolethal distending toxin B Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- IA
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16293
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87417-2 | Cytolethal distending toxin B and Vinculin Ab panel - Serum by Immunoassay |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Cytoletální distenční toxin B Ab: |
| el-GR | Greek (Greece) | Κυτταρολεθρική διογκούμενη τοξίνη Β Αντίσωμα: Synonyms: ACnc B IA Pt Qn SERO Αντίσωμα Κυτταρολεθρική διογκούμενη τοξίνη Β Ορός |
| es-ES | Spanish (Spain) | toxina B de Cytolethal distending Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Toxina de distensión citoletal B Ab: |
| fr-FR | French (France) | Toxine cytoléthale B Ac: |
| it-IT | Italian (Italy) | Cytolethal distending toxin B Ab: Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| zh-CN | Chinese (China) | 细胞致死膨胀毒素 B 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
87420-6 Vinculin Ab [Units/volume] in Serum by Immunoassay
Part Descriptions
LP71770-9 Vinculin Ab
Vinculin (VCL) is classified as a cytoskeletal protein that is believed to function as an anchor to F-actin and the cell membrane. Antibodies against cytolethal distending toxin B Ab (CtdB Ab) can cross react with vinculin. Vinculin and CdtB antibodies are useful as biomarkers for irritable bowel syndrome with diarrhea (D-IBS) and may help distinguish D-IBS from inflammatory bowel disease in the workup of chronic diarrhea. PMID: 25970536
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Vinculin Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
- IA
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16303
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87417-2 | Cytolethal distending toxin B and Vinculin Ab panel - Serum by Immunoassay |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Vinculin Ab: |
| el-GR | Greek (Greece) | Βινκουλίνη Αντίσωμα: Synonyms: ACnc IA Pt Qn SERO Αντίσωμα Βινκουλίνη Ορός |
| es-ES | Spanish (Spain) | Vinculina Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Vinculin Ab: |
| et-EE | Estonian (Estonia) | Vinkuliin antikehad: Synonyms: Juhuslik Kvantitatiivne Seerum |
| fr-FR | French (France) | Vinculine Ac: |
| fr-CA | French (Canada) | Vinculine, Ac: |
| fr-BE | French (Belgium) | Vinculine Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Vinculina Ab: Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | vinculine As: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | Винкулин Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Vinkulin Ab: Synonyms: Ak İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 粘着斑蛋白 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
87419-8 Cytolethal distending toxin B+Vinculin Ab [Interpretation] in Serum Qualitative by Immunoassay
Term Description
Cytolethal distending toxin B (CdtB) and vinculin antibodies are useful as biomarkers for irritable bowel syndrome with diarrhea (D-IBS) in humans. Studies suggest that elevated levels of vinculin antibodies are more commonly found in patients with D-IBS than those with other forms of inflammatory bowel disease (IBD) and may help distinguish the two. PMID: 25970536 This term was created for, but is not limited in use to, the Quest Diagnostics' IBSDetex assay.
Fully-Specified Name
- Component
- Cytolethal distending toxin B+Vinculin Ab
- Property
- Imp
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16302
Example Answer List LL4669-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Inconsistent with IBS | LA28184-2 | ||
| Consistent with IBS | LA28185-9 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87417-2 | Cytolethal distending toxin B and Vinculin Ab panel - Serum by Immunoassay |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Cytoletální distenční toxin B+vinculin Ab: |
| el-GR | Greek (Greece) | Κυτταρολεθρική διογκούμενη τοξίνη Β+Βινκουλίνη Αντίσωμα: Synonyms: B IA Imp Ord Pt SERO Αντίσωμα Βινκουλίνη Κυτταρολεθρική διογκούμενη τοξίνη Β Κυτταρολεθρική διογκούμενη τοξίνη Β+Βινκουλίνη Ορός |
| es-ES | Spanish (Spain) | toxina B de Cytolethal distending +Vinculin Anticuerpos: |
| es-MX | Spanish (Mexico) | Toxina de distensión citoletal B + Vinculina Ab: |
| fr-FR | French (France) | Toxine cytoléthale B anticorps + vinculine Ac: |
| it-IT | Italian (Italy) | Cytolethal distending toxin B+ Ab: Synonyms: anticorpo Immunoassay Impressione/interpretazione di studio Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| pl-PL | Polish (Poland) | Cytotoksyczna rozciągająca toksyna B+Winkulina Ab: Synonyms: Cytotoksyczna rozszerzająca toksyna B i winkulina; |
| zh-CN | Chinese (China) | 细胞致死膨胀毒素 B+粘着斑蛋白 抗体: Synonyms: Ab; |