87424-8
Cytomegalovirus IgG and IgM panel - Serum or Plasma Qualitative
Active
22244-8 Cytomegalovirus IgG Ab [Presence] in Serum or Plasma
Part Descriptions
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- CMV IgG SerPl Ql
- Display Name
- CMV IgG Ql
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV) IgG antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0n
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser since this test can be performed on plasma specimens as well.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5193
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87424-8 | Cytomegalovirus IgG and IgM panel - Serum or Plasma Qualitative |
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 75868-0 | HEDIS 2015 Value Sets |
| 79544-3 | HEDIS 2016 Value Sets |
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CMV-AK IgG |
| de-DE | German (Germany) | Cytomegalie-Virus Ak.IgG: Synonyms: CMV |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] citomegalovirus [Ac].IgG [Inmunoglobulina G]: |
| es-MX | Spanish (Mexico) | Citomegalovirus Ab.IgG: |
| es-ES | Spanish (Spain) | Citomegalovirus IgG: |
| et-EE | Estonian (Estonia) | Tsütomegaloviirus antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Cytomégalovirus, IgG: |
| fr-BE | French (Belgium) | Cytomégalovirus Anticorps. IgG: Synonyms: Anticorps CMV |
| fr-FR | French (France) | Cytomégalovirus Ac IgG: |
| it-IT | Italian (Italy) | Citomegalovirus Ab.IgG: Synonyms: anticorpi IgG anticorpo Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 거대세포바이러스 항체.면역글로불린 G: |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus As.IgG: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus cytomegalii Ab.IgG: Synonyms: Cytomegalowirus IgG Przecwciała do cytomegalowirusa Przecwciała IgG do cytomegalowirusa |
| pt-BR | Portuguese (Brazil) | Citomegalovírus Ac.IgG: Synonyms: Immune globulin G; |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус Ат.IgG: Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus Ab.IgG: Synonyms: Ak Ak.IgG Mevcut |
| zh-CN | Chinese (China) | 巨细胞病毒 抗体.IgG: Synonyms: Ab.IgG; |
30325-5 Cytomegalovirus IgM Ab [Presence] in Serum or Plasma
Part Descriptions
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus Ab.IgM
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- CMV IgM SerPl Ql
- Display Name
- CMV IgM Ql
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV) IgM antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.04
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser since this test can be performed on plasma specimens as well.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5373
Example Answer List LL2009-0
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Equivocal Copyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value) | LA11885-3 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 87424-8 | Cytomegalovirus IgG and IgM panel - Serum or Plasma Qualitative |
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 75868-0 | HEDIS 2015 Value Sets |
| 79544-3 | HEDIS 2016 Value Sets |
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CMV-AK IgM |
| de-DE | German (Germany) | Cytomegalie-Virus Ak.IgM: Synonyms: CMV |
| es-ES | Spanish (Spain) | Citomegalovirus IgM: |
| es-MX | Spanish (Mexico) | Citomegalovirus Ab.IgM: |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] citomegalovirus [Ac].IgM [Inmunoglobulina M]: |
| et-EE | Estonian (Estonia) | Tsütomegaloviirus antikehad.IgM: Synonyms: Immuunglobuliin M Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Cytomégalovirus, IgM: |
| fr-FR | French (France) | Cytomégalovirus Ac IgM: |
| fr-BE | French (Belgium) | Cytomégalovirus Anticorps. IgM: Synonyms: Anticorps CMV |
| it-IT | Italian (Italy) | Citomegalovirus Ab.IgM: Synonyms: Anticorpi IgM anticorpo Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 거대세포바이러스 항체.면역글로불린 M: |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus As.IgM: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus cytomegalii Ab.IgM: Synonyms: Cytomegalowirus IgM Przecwciała do cytomegalowirusa Przecwciała IgM do cytomegalowirusa |
| pt-BR | Portuguese (Brazil) | Citomegalovírus Ac.IgM: Synonyms: Immune globulin M; |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус Ат.IgM: Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus Ab.IgM: Synonyms: Ak Ak.IgM Mevcut |
| zh-CN | Chinese (China) | 巨细胞病毒 抗体.IgM: Synonyms: Ab.IgM; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
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