87609-4
Dicoumarol [Mass/mass] in Specimen
Active
Term Description
Possible samples include animal liver, kidney, or other tissue, and a wide variety of animal feed.
Part Description
LP16112-2 Dicoumarol
Dicoumarol (International Nonproprietary Name) or dicumarol (United States Adopted Name) is an anticoagulant that functions as a Vitamin K antagonist (similar to warfarin, for which it was the inspiration). It is also used in biochemical experiments as an inhibitor of reductases.
Dicoumarol is a natural chemical substance of combinded plant and fungal origin. It is a derivative of coumarin, a substance made by plants that does not itself affect coagulation, but which is (classically) transformed in mouldy feeds by a number of species of fungi into active dicoumarol. Dicoumarol does affect coagulation, and was discovered in mouldy wet sweet-clover hay, as the agent of a naturally occurring bleeding disease in cattle.
It is given only orally, and it acts within two days.
Mechanism of action : it is a competitive inhibitor of Vitamin K preventing the formation of prothrombin. Administration of Vitamin K is the antidote for dicoumarol toxicity. Follow-up is done by measuring the prothrombin time (PT).
Uses: Used along with heparin for the treatment of deep venous thrombosis
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Source: Wikipedia,
Wikipedia
LOINC Names Get Info
- Fully-Specified Name
- Dicoumarol:
MCnt: Pt: XXX: Qn: - Long Common Name
- Dicoumarol [Mass/mass] in Specimen
- Short Name
- Dicoumarol Spec-mCnt
- Display Name
- Dicoumarol (Specimen) [Mass/Mass]
- Consumer Name Alpha Get Info
- Dicoumarol, Specimen
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.69 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Dikumarol: |
| el-GR | Greek (Greece) | Δικουμαρόλη: Synonyms: DRUG/TOX MCnt Pt Qn XXX Δικουμαρόλη |
| es-ES | Spanish (Spain) | Dicumarol: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Dicumarol: |
| et-EE | Estonian (Estonia) | Dikumarool: Synonyms: Juhuslik Kvantitatiivne Täpsustamata materjal |
| fr-CA | French (Canada) | Dicoumarol: |
| fr-FR | French (France) | Dicoumarol: |
| fr-BE | French (Belgium) | Dicoumarol: |
| it-IT | Italian (Italy) | Dicoumarol: Synonyms: Contenuto di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | dicoumarol: |
| ru-RU | Russian (Russian Federation) | Дикумарол: Synonyms: Количественный Масса содержание Точка во времени; |
| tr-TR | Turkish (Turkey) | Dikumarol: |
| zh-CN | Chinese (China) | 双香豆素: Synonyms: 不明的; |
Example Units
| Unit | Source |
|---|---|
| mg/kg; [ppm] | Example UCUM Units |
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