87711-8
Rotavirus B VP7 gene [Nucleotide sequence] in Isolate by Sequencing
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Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP263555-7 Rotavirus B VP7 gene
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus B (RVB) infect both humans and animals, and were the cause of severe diarrheal epidemics in China between 1982 and 1987. RVB has been isolated in lambs, pigs, cattle, goats and rats. India, Bangladesh, and Myanmar have also experienced acute outbreaks of gastroenteritis caused by infection with RVB. PMID: 2556635http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub PMID: 21985827 PMID: 24155654
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Rotavirus B VP7 gene:
Seq: Pt: Isolate: Nom: Sequencing - Long Common Name
- Rotavirus B VP7 gene [Nucleotide sequence] in Isolate by Sequencing
- Short Name
- RVB VP7 Islt-Seq
- Display Name
- Rotavirus B VP7 gene sequence Nom (Isol)
- Consumer Name Alpha Get Info
- Rotavirus B VP7 gene
Part Model Get Info
- Component
- Rotavirus B VP7 gene
LP263555-7
- Analyte
- Rotavirus B VP7 gene
LP263555-7
- Component Numerator
- Rotavirus B VP7 gene
LP263555-7
- Component Numerator Core
- Rotavirus B VP7 gene
LP263555-7
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Seq
LP62164-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Isolate
LP7370-2
- System Core
- Isolate
LP7370-2
- Super System
- NULL
- Scale
- Nom
LP7750-5
- Method
- Sequencing
LP150045-5
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.64 (MIN)
- Change Reason
- Abbreviated "Rotavirus B" to "RVB" in the Shortname for consistency across terms.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Rotavirus B gen VP7: |
| de-DE | German (Germany) | Rotavirus B VP7-Gen: |
| el-GR | Greek (Greece) | Γονίδιο ροταϊού Β VP7: Synonyms: B MICRO Nom Pt Seq Αλληλούχιση Απομονωμένο στέλεχος Γονίδιο Γονίδιο ροταϊού Β VP7 Ροταϊός Ροταϊός B |
| es-ES | Spanish (Spain) | Gen VP7 rotavirus B: |
| es-MX | Spanish (Mexico) | Gen VP7 del rotavirus B: |
| fr-FR | French (France) | Rotavirus B gène VP7: |
| it-IT | Italian (Italy) | Rotavirus B, gene VP7: Synonyms: Microbiologia Punto nel tempo (episodio) Sequenza nucleotidica |
| nl-NL | Dutch (Netherlands) | Rotavirus B VP7-gen: |
| pl-PL | Polish (Poland) | Rotavirus B VP7 gen: Synonyms: Gen VP7 Rotawirusa grupy B wynik kategorialny |
| zh-CN | Chinese (China) | 轮状病毒 B VP7 基因: Synonyms: B 型 ROTAV; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://