Version 2.78

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP206581-3   Influenza virus A M gene
The matrix protein gene of influenza virus A encodes two proteins: a matrix protein (M1) and an ion channel protein (M2). M1 plays a critical role in virus structure and replication by building connections between the viral lipid membrane and ribonucleoprotein (RNP) core. M1 also binds to RNPs in the nucleus, inhibiting viral transcription. The ion channel (M2) protein spans the lipid bilayer. Source: Regenstrief LOINC

LP206581-3   Influenza virus A M gene
The influenza virus A (FLUVA) genome is composed of eight gene segments (PB2, PB1, PA, HA, NP, NA, M, NS1) that code for 11 proteins. Two of the genes, hemagglutinin (HA) and neuraminidase (NA), determine the structure of the two primary surface proteins of influenza viruses. The HA and NA gene sequences are used to determine the Influenza virus subtype. Currently there are 16 subtypes of HA and 9 subtypes of NA known, but only H 1, 2 and 3, and N 1 and 2 are commonly found in humans. PMID: 17458769 The M gene segment, which encodes two matrix proteins (M1 and M2), may also be used as a target in PCR-based assays for detection of FLUVA in various specimens. Source: Regenstrief LOINC

LP206581-3   Influenza virus A M gene
The influenza A virus (FLUAV) is a common respiratory virus that infects humans as well as birds, horses, seals, dogs, and pigs. There are eight gene segments that make up the negative single-stranded RNA of the FLUAV. The gene segments are known as PB1, PB2, PA, NP, HA, NA, M, and NS. The M gene is the seventh segment and encodes the M1 (matrix protein) and M2 (membrane) proteins. [https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-6-67] The M1 protein is located beneath the lipid membrane and functions to give support and strength to the viral envelope. The M2 transmembrane protein is an ion channel that assists to uncover the virus once it is inside the host cell. M1 and NP proteins together determine whether the influenza virus is type A, B, or C. M1 brings viral constituents together to the assembly location, playing important roles in the creation of viral particles and in the budding process.[http://www.clinlabnavigator.com/influenza-virus-subtypes.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A M gene
Property
Seq
Time
Pt
System
Isolate
Scale
Nom
Method
Sequencing

Additional Names

Long Common Name
Influenza virus A M gene [Nucleotide sequence] in Isolate by Sequencing
Short Name
FLUAV M gene Islt-Seq
Display Name
FLUAV M gene sequence Nom (Isol)
Consumer Name Alpha Get Info
Influenza A M gene

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A M-Gen:Sequenz:Zeitpunkt:Isolat:Nominal:Sequenzierung
es-ES Spanish (Spain) Genes A+B Metapneumovirus humano:Secuencia de nucleótidos:Punto temporal:Aislado:Nom:Secuenciación
es-MX Spanish (Mexico) Gen A M del virus de la influenza:Secuencia de nucleótidos:Punto temporal:Aislado:Nominal:Secuenciación
fr-FR French (France) Influenza virus A gène M:Séquence nucléotidique:Ponctuel:Isolat:Résultat nominal:Séquençage
it-IT Italian (Italy) Virus Influenza A gene M:Seq:Pt:Isolato:Nom:Sequenziamento
Synonyms: Microbiologia Punto nel tempo (episodio) Sequenza nucleotidica Virus dell''influenza Virus dell''influenza A
nl-NL Dutch (Netherlands) Influenzavirus A M-gen:nucleotidevolgorde:moment:isolaat:nominaal:sequencing
Synonyms: Influenza virus A M gen
pl-PL Polish (Poland) Influenza wirus A gen M:sekwencja nukleotydu:punkt w czasie:izolat:cecha:sekwencjonowanie
Synonyms: Gen M wirusa grypy typu A Wirus grypy Wirus grypy typ A
zh-CN Chinese (China) 流感病毒 A 型 M 基因:序列:时间点:分离株:名义型:序列测定
Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 FLUV;Influ;列性感冒病毒;流行性感冒病毒 M 型 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 核苷酸序列 流行性感冒病毒 A 型 M 基因;甲型流感病毒 M 基因 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87714-2