Version 2.77

Part Descriptions

LP172561-5   Ceftolozane+Tazobactam
Ceftolozane/tazobactam is a first-line IV therapy for the treatment of certain serious Gram-negative bacterial infections, including those caused by multi-drug resistant Pseudomonas aeruginosa. Source: Regenstrief LOINC

LP172561-5   Ceftolozane+Tazobactam
Ceftolozane is a cephalosporin with powerful activity against Gram-negative bacteria including Pseudomonas aeruginosa and Enterobacteriaceae.[http://aac.asm.org/content/57/4/1577.full] Tazobactam is a beta lactamase inhibitor and penicillin derivative that is effective against beta-lactamase-producing bacteria.[PubChem: 123630] Ceftolozane blocks penicillin binding proteins which disrupts bacterial cell-wall synthesis that leads to bacterial cell death. When tazobactam is added to ceftolozane, there is a broader spectrum of antimicrobial activity against resistant strains including extended spectrum beta-lactamases (ESBLs).Tazobactam prevents class A beta-lactamases and some class C beta-lactamases from hydrolyzing ceftolozane. Together, ceftolozane+tazobactam are an effective treatment for complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia. PMID: 25516692 Source: Regenstrief LOINC

LP6300-0   Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ceftolozane+Tazobactam
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
Gradient strip

Additional Names

Short Name
Ceftolozane+Tazobactam Islt Grad strip
Display Name
Ceftolozane+Tazobactam Strip [Susc]
Consumer Name Alpha Get Info
Susceptibility to Ceftolozane+Tazobactam

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG41460-3 Ceftolozane+TazobactamSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Ceftolozan+Tazobactam:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Gradientenstreifen
es-ES Spanish (Spain) Ceftolozane+Tazobactam:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Tira de gradiente (E-prueba)
es-MX Spanish (Mexico) Ceftolozano + Tazobactam:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Tira de degradado
fr-FR French (France) Ceftolozane+tazobactam:Sensibilité:Ponctuel:Isolat:Alphanumérique:Bandelette graduée
it-IT Italian (Italy) Ceftolozane+Tazobactam:Susc:Pt:Isolato:OrdQn:Gradiente striscia
Synonyms: Gradiente striscia (E-test) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) ceftolozaan + tazobactam:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:gradiëntstrip
ru-RU Russian (Russian Federation) Цефтолозан+Тазобактам:Чув:ТчкВрм:Изолят:ПорКол:Градиентная полоска
Synonyms: Градиентная полоска (Е-тест) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Seftolozan+Tazobaktam:Duyr:Zmlı:İzolat:SrlKant:Gradiyent çubuğu
zh-CN Chinese (China) 头孢洛林+他唑巴坦:抗生素敏感性:时间点:分离株:定量型或序数型:梯度胶条法
Synonyms: 3a-甲基-7-氧代-3b-(1H-1,2,3,-三唑-1-亚甲基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2a-羧酸4，4-二氧化物;他左巴坦;他巴克坦;青霉烷砜类 Beta-内酰胺酶抑制剂;青霉烷砜类β-内酰胺酶抑制剂 E-胶条法;E-试验;E-试验法;梯度条;梯度条法;梯度板条;梯度板条法;梯度胶条;梯度胶片;梯度胶片法;E-胶条 三唑巴坦 分离物;分离菌;分离菌株;隔离种群 头孢洛林（头孢洛林酯、头孢他诺林、头孢他洛林酯、头孢他洛林）+他唑巴坦（他左巴坦、他巴克坦） 巴坦 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

Example Units

Unit Source
ug/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87735-7