87735-7
Ceftolozane+Tazobactam [Susceptibility] by Gradient strip
Active
Part Descriptions
LP172561-5 Ceftolozane+Tazobactam
Ceftolozane/tazobactam is a first-line IV therapy for the treatment of certain serious Gram-negative bacterial infections, including those caused by multi-drug resistant Pseudomonas aeruginosa.
Source: Regenstrief LOINC
LP172561-5 Ceftolozane+Tazobactam
Ceftolozane is a cephalosporin with powerful activity against Gram-negative bacteria including Pseudomonas aeruginosa and Enterobacteriaceae.http://aac.asm.org/content/57/4/1577.full Tazobactam is a beta lactamase inhibitor and penicillin derivative that is effective against beta-lactamase-producing bacteria.[PubChem: 123630] Ceftolozane blocks penicillin binding proteins which disrupts bacterial cell-wall synthesis that leads to bacterial cell death. When tazobactam is added to ceftolozane, there is a broader spectrum of antimicrobial activity against resistant strains including extended spectrum beta-lactamases (ESBLs).Tazobactam prevents class A beta-lactamases and some class C beta-lactamases from hydrolyzing ceftolozane. Together, ceftolozane+tazobactam are an effective treatment for complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia. PMID: 25516692
Source: Regenstrief LOINC
LP6300-0 Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Ceftolozane+Tazobactam:
Susc: Pt: Isolate: OrdQn: Gradient strip - Long Common Name
- Ceftolozane+Tazobactam [Susceptibility] by Gradient strip
- Short Name
- Ceftolozane+Tazobactam Islt Grad strip
- Display Name
- Ceftolozane+Tazobactam Strip [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Ceftolozane+Tazobactam
Part Model Get Info
- Component
- Ceftolozane+Tazobactam
LP172561-5
- Analyte
- Ceftolozane+Tazobactam
LP172561-5
- Component Numerator
- Ceftolozane+Tazobactam
LP172561-5
- Component Numerator Core
- Ceftolozane+Tazobactam
LP172561-5
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Susc
LP6870-2
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Isolate
LP7370-2
- System Core
- Isolate
LP7370-2
- Super System
- NULL
- Scale
- OrdQn
LP7752-1
- Method
- Gradient strip
LP6300-0
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.63 (ADD)
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG41460-3 | Ceftolozane+TazobactamSusc| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Ceftolozan+tazobaktam: |
| de-DE | German (Germany) | Ceftolozan+Tazobactam: |
| el-GR | Greek (Greece) | Κεφτολοζάνη+Ταζομπακτάμη: Synonyms: ABXBACT OrdQn Pt Susc Απομονωμένο στέλεχος Κεφτολοζάνη+Ταζομπακτάμη Λωρίδα με διαβαθμίσεις Ταζομπακτάμη |
| es-ES | Spanish (Spain) | Ceftolozane+Tazobactam: |
| es-MX | Spanish (Mexico) | Ceftolozano + Tazobactam: |
| fr-FR | French (France) | Ceftolozane+tazobactam: |
| it-IT | Italian (Italy) | Ceftolozane+Tazobactam: Synonyms: Gradiente striscia (E-test) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | ceftolozaan + tazobactam: |
| ru-RU | Russian (Russian Federation) | Цефтолозан+Тазобактам: Synonyms: Градиентная полоска (Е-тест) Порядковый или Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Seftolozan+Tazobaktam: |
| zh-CN | Chinese (China) | 头孢洛林+他唑巴坦: Synonyms: 3a-甲基-7-氧代-3b-(1H-1,2,3,-三唑-1-亚甲基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2a-羧酸4, |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://