LOINC
Version 2.73

88018-7Alanine/Lysine [Mass Ratio] in DBSActive

Term Description

Elevated alanine levels is suggestive of a metabolic disorder. Since alanine levels can fluctuate depending on dietary intake, the alanine to lysine ratio is used to adjust for dietary variation. Normal alanine to lysine ratio is less than 3:1. An elevated alanine along with a elevated alaine:lysine ratio (>3) suggests true hyperalaninemia.[PMID:18243024]
Source: Regenstrief LOINC

Part Descriptions

LP15331-9   Alanine
Alanine is a non-essential amino acid that exists as two distinct enantiomers: L-alanine and D-alanine. Alanine is one of the primary amino acids (secondary to leucine) used for protein construction. It is produced from pyruvate, exists in high levels in plasma, and is involved in the metabolism of sugar and organic acids.[PubChem:Alanine] Alanine acts as a substrate for alanine aminotransferase (ALT), an enzyme commonly measured to determine liver health. Increased alanine levels are seen in patients with lactic acidosis, carbamoyl phosphate synthetase deficiency, histidinemia, hyperprolinemia, and ornithine transcarbamylase deficiency. In patients with a mitochondrial disease, elevated alanine levels are primarily seen during times of physiologic stress or regression.[PMID:18243024] Source: Regenstrief LOINC

LP263693-6   Lysine
Lysine is an essential basic amino acid that plays a major role in calcium absorption and the production of hormones, enzymes, and antibodies. Lack of lysine can result in niacin deficiency and cause the pellagra. Other diseases associated with lysine include hyperlysinemia, lysine intolerance, carbamoyl phosphate synthetase deficiency, and saccharopinuria (saccharopine is an intermediate in the metabolism of lysine). Source: Regenstrief Institute

Fully-Specified Name

Component
Alanine/Lysine
Property
MRto
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Short Name
Alanine/Lysine DBS
Display Name
Alanine/Lysine (DBS) [Mass ratio]
Consumer Name Alpha
Alanine/Lysine, Dried blood spot

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
丙氨酸/赖氨酸:质量比率:时间点:全血.斑点:定量型:
fr-FRFrench (France)
Alanine/lysine:Masse ratio:Ponctuel:Sang buvard:Numérique:
it-ITItalian (Italy)
Alanina/Lisina:MRto:Pt:Sangue.su carta da filtro:Qn:
es-MXSpanish (Mexico)
Alanina / Lisina:Relación de masa:Punto temporal:DBS:Cuantitativo:
es-ESSpanish (Spain)
Alanina/Lisina:Relacion de Masa:Punto temporal:gota de sangre (papel de filtro):Qn:

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88018-7