88131-8
Cytomegalovirus DNA [Presence] in Ocular fluid by NAA with probe detection
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Part Descriptions
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html
Source: Regenstrief LOINC
LP7448-6 Ocular fld
The "Ocular fld" System in LOINC encompasses aqueous humor and vitreous humor. Aqueous humor is found in the anterior and posterior chambers of the eye, both of which are located anterior to the lens. Vitreous humor is found in the vitreous chamber, which is located between the lens and the retina. This System is used for LOINC terms that represent tests run on either aqueous or vitreous fluid; it does not imply that both types of fluid are tested in any given instance.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Cytomegalovirus DNA:
PrThr: Pt: Ocular fld: Ord: Probe.amp.tar - Long Common Name
- Cytomegalovirus DNA [Presence] in Ocular fluid by NAA with probe detection
- Short Name
- CMV DNA Ocflu Ql NAA+probe
- Display Name
- CMV DNA NAA+probe Ql (Ocular fluid)
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV), Eye fluid
Part Model Get Info
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.63 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Cytomegalovirus DNA: |
| de-DE | German (Germany) | Cytomegalie-Virus DNA: Synonyms: CMV; |
| el-GR | Greek (Greece) | Κυτταρομεγαλοϊός DNA: Synonyms: DNA MICRO Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Κυτταρομεγαλοϊός Οφθαλμικό υγρό |
| es-ES | Spanish (Spain) | Citomegalovirus ADN: |
| es-MX | Spanish (Mexico) | ADN de citomegalovirus: |
| fr-CA | French (Canada) | Cytomégalovirus, ADN: |
| fr-FR | French (France) | Cytomégalovirus ADN: |
| fr-BE | French (Belgium) | Cytomégalovirus ADN: Synonyms: CMV |
| it-IT | Italian (Italy) | Citomegalovirus DNA: Synonyms: Liquido oculare Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus DNA: Synonyms: probe.amp.tar |
| pl-PL | Polish (Poland) | Wirus cytomegalii DNA: Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус ДНК: Synonyms: ДНК проба; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus DNA: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 巨细胞病毒 DNA: Synonyms: CMV DNA CMV; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://