Version 2.78

Term Description

Used to determine HIV 1 RNA resistance in CSF samples from patients with neurological symptoms of HIV who may have CSF/plasma discordance in the amount of circulating virus as well as resistance patterns. PMID: 25344810
Source: Regenstrief LOINC

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component
HIV 1 RNA integrase gene mutations detected
Property
Prid
Time
Pt
System
CSF
Scale
Nom
Method
Sequencing

Additional Names

Short Name
HIV 1 RNA IN Mut Det CSF Seq
Display Name
HIV 1 RNA IN mutations detected Sequencing Nom (CSF)
Consumer Name Alpha Get Info
HIV 1 RNA IN variant analysis, Spinal fluid

Example Answer List: LL3697-1

Source: Laboratory Corporation of America
Answer Code Score Answer ID
V31I

HIV mutation in the integrase (IN) coding region

 LA19757-6
V72I

HIV mutation in the integrase (IN) coding region

 LA24443-6
T97A

HIV mutation in the integrase (IN) coding region

 LA24440-2
L101I

HIV mutation in the integrase (IN) coding region

 LA24444-4
V113I

HIV mutation in the integrase (IN) coding region

 LA24445-1
S119S/T

HIV mutation in the integrase (IN) coding region

 LA24442-8
T124A

HIV mutation in the integrase (IN) coding region

 LA24446-9
E138D

HIV mutation in the integrase (IN) coding region

 LA24447-7
Y143R

HIV mutation in the integrase (IN) coding region

 LA24441-0
E157E/Q

HIV mutation in the integrase (IN) coding region

 LA24449-3
K188R

HIV mutation in the integrase (IN) coding region

 LA24450-1
G193E

HIV mutation in the integrase (IN) coding region

 LA24451-9
V201I

HIV mutation in the integrase (IN) coding region

 LA24452-7
V234L

HIV mutation in the integrase (IN) coding region

 LA24453-5
D288N

HIV mutation in the integrase (IN) coding region

 LA24454-3

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen integrasa VIH1 RNA Detección de mutaciones:Presencia o identidad:Punto temporal:Líquido Cefalorraquideo:Nom:Secuenciación
es-MX Spanish (Mexico) Se detectaron mutaciones en el gen de la integrasa del ARN del VIH 1:Presencia o identidad:Punto temporal:Fluído espinal cerebral:Nominal:Secuenciación
fr-FR French (France) VIH-1 ARN gène intégrase mutations détectées:Identification:Ponctuel:Liquide céphalorachidien:Résultat nominal:Séquençage
it-IT Italian (Italy) HIV 1, RNA gene integrasi, mutazioni identificate:Prid:Pt:LCS:Nom:Sequenziamento
Synonyms: Liquido cerebrospinale Presenza o Identità Punto nel tempo (episodio) RNA dell''HIV 1 Suscettibilità agli antibiotici
zh-CN Chinese (China) HIV 1 型 RNA 整合酶基因 已检出的突变:存在与否或特征标识:时间点:脑脊液:名义型:序列测定
Synonyms: Ⅰ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） RNA 整合酶（IN）基因 HIV1 RNA HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 已发现的突变 序列分析;测序 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 突变 突变类;基因突变 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88542-6