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Term Description

Used to determine HIV 1 RNA resistance in CSF samples from patients with neurological symptoms of HIV who may have CSF/plasma discordance in the amount of circulating virus as well as resistance patterns. PMID: 25344810

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
HIV 1 RNA protease gene mutations detected:Prid:Pt:CSF:Nom:Sequencing
Long Common Name
HIV 1 RNA protease gene mutations detected [Identifier] in Cerebrospinal Fluid by Sequencing
Short Name
HIV 1 RNA PR Mut Det CSF Seq
Display Name
HIV 1 RNA PR mutations detected Sequencing Nom (CSF)
Consumer Name Alpha Get Info
HIV 1 RNA PR variant analysis, Spinal fluid

Part Model Get Info

  • Component
    HIV 1 RNA protease gene mutations detected
    LP265771-8
    • Analyte
      HIV 1 RNA protease gene mutations detected
      LP265771-8
      • Component Numerator
        HIV 1 RNA protease gene mutations detected
        LP265771-8
        • Component Numerator Core
          HIV 1 RNA protease gene
          LP265772-6
        • Component Numerator Core Suffix
          mutations detected
          LP32420-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Sequencing
    LP150045-5

Example Answer List: LL4855-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
I62V

HIV mutation in the protease (PR) coding region

LA19758-4
Q18K

HIV mutation in the protease (PR) coding region

LA25851-9
E35D

HIV mutation in the protease (PR) coding region

LA25852-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)HIV 1 RNA proteáza genové mutace detekované:Přítomnost nebo identita:Časový bod:Mozkomíšní mok:Nominální:Sekvenace
el-GRGreek (Greece)Γονίδιο πρωτεάσης RNA του ιού της ανθρώπινης ανοσοανεπάρκειας 1 ανιχνευθείσες μεταλλάξεις:Prid:Pt:ΕΝΥ:Nom:Αλληλούχιση
Synonyms: ABXBACT HIV 1 Nom Prid Pt RNA RNA ιού της ανθρώπινης ανοσοανεπάρκειας 1 Αλληλούχιση ανιχνευθείσες μεταλλάξεις Γονίδιο Γονίδιο πρωτεάσης RNA του ιού της ανθρώπινης ανοσοανεπάρκειας 1 ΕΝΥ Ιός ανθρώπινης ανοσοανεπάρκειας Μεταλλάξεις
es-ESSpanish (Spain)Gen proteasa VIH1 RNA Detección de mutaciones:Presencia o identidad:Punto temporal:Líquido Cefalorraquideo:Nom:Secuenciación
es-MXSpanish (Mexico)Se detectaron mutaciones en el gen de la proteasa del ARN del VIH 1:Presencia o identidad:Punto temporal:Fluído espinal cerebral:Nominal:Secuenciación
fr-FRFrench (France)VIH-1 ARN gène de la protéase mutations détectées:Identification:Ponctuel:Liquide céphalorachidien:Résultat nominal:Séquençage
it-ITItalian (Italy)HIV 1 RNA, gene proteasi, mutazioni identificate:Prid:Pt:LCS:Nom:Sequenziamento
Synonyms: Liquido cerebrospinale Presenza o Identità Punto nel tempo (episodio) RNA dell''HIV 1 Suscettibilità agli antibiotici
pl-PLPolish (Poland)Proteaza HIV 1 RNA gen wykryte mutacje:obecność lub identyfikacja:punkt w czasie:płyn mózgowo-rdzeniowy:skala nominalna:sekwencjonowanie
Synonyms: Gen proteazy RNA ludzkiego wirusa niedoboru odporności typu 1;Gen proteazy RNA HIV 1 Ludzki wirus niedoboru odporności Ludzki wirus niedoboru odporności typu 1 RNA ludzkiego wirusa niedoboru odporności typu 1 wynik kategorialny
zh-CNChinese (China)HIV 1 型 RNA 蛋白酶基因 已检出的突变:存在与否或特征标识:时间点:脑脊液:名义型:序列测定
Synonyms: Ⅰ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） RNA 蛋白酶（Prot）基因 HIV1 RNA HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 已发现的突变 序列分析;测序 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 朊酶 核糖核酸;Ribonucleic acid 突变 突变类;基因突变 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 蛋白质酵素 遗传基因;遗传因子;吉恩;生物基因

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https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88543-4