88567-3
Cytomegalovirus DNA [Presence] in Bone marrow by NAA with probe detection
Active
Part Description
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus DNA
- Property
- PrThr
- Time
- Pt
- System
- Bone mar
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- CMV DNA Mar Ql NAA+probe
- Display Name
- CMV DNA NAA+probe Ql (BM)
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV), Bone marrow
Example Answer List: LL1937-3
Source: 3M Health Information Systems| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.65
- Change Reason
- Updated System from "Bone marrow" for consistency across Lab terms
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Cytomegalie-Virus DNA: Synonyms: CMV |
| es-ES | Spanish (Spain) | Citomegalovirus ADN: |
| es-MX | Spanish (Mexico) | ADN de citomegalovirus: |
| fr-BE | French (Belgium) | Cytomégalovirus ADN: Synonyms: CMV |
| fr-CA | French (Canada) | Cytomégalovirus, ADN: |
| fr-FR | French (France) | Cytomégalovirus ADN: |
| it-IT | Italian (Italy) | Citomegalovirus DNA: Synonyms: Microbiologia Midollo osseo Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus DNA: Synonyms: probe.amp.tar |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус ДНК: Synonyms: ДНК проба; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus DNA: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 巨细胞病毒 DNA: Synonyms: CMV DNA CMV; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=88567-3
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