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Part Description

LP207328-8   Bedaquiline
Bedaquiline (trade name Sirturo) is a diarylquinoline anti-tuberculosis drug. When it was approved by the U.S. FDA in 2012, it was the first time in 40 years that a drug with a different mechanism of action compared to the existing TB treatments had been approved, and it is specifically approved to treat adults with pulmonary multi-drug resistant tuberculosis (MDR TB) and extensively drug resistant tuberculosis (XDR TB). Badaquiline should only be used when an effective treatment regimen cannot otherwise be provided. The most common side effects of bedaquiline in studies were nausea, joint and chest pain, and headache, however the drug also has a black-box warning for life-threatening arrhythmias, as it may induce long QT syndrome by blocking the hERG channel. PMID: 23776831 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Bedaquiline:Susc:Pt:Isolate:OrdQn:MIC
Long Common Name
Bedaquiline [Susceptibility] by Minimum inhibitory concentration (MIC)
Short Name
Bedaquiline Islt MIC
Display Name
Bedaquiline MIC [Susc]
Consumer Name Alpha Get Info
Susceptibility to Bedaquiline

Part Model Get Info

  • Component
    Bedaquiline
    LP207328-8
    • Analyte
      Bedaquiline
      LP207328-8
      • Component Numerator
        Bedaquiline
        LP207328-8
        • Component Numerator Core
          Bedaquiline
          LP207328-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Susc
    LP6870-2
  • Time
    Pt
    LP6960-1
  • System
    Isolate
    LP7370-2
    • System Core
      Isolate
      LP7370-2
    • Super System
      NULL
       
  • Scale
    OrdQn
    LP7752-1
  • Method
    MIC
    LP6389-3

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64 (ADD)
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC GroupGroup Name
LG41784-6BedaquilineSusc|Isolate

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Bedachilin:Citlivost (mikroorganismy):Časový bod:Izolát:Ordinální nebo kvantitativní:Minimální inhibiční koncentrace (MIC)
de-DEGerman (Germany)Bedaquilin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Minimale Hemmkonzentration (MHK)
el-GRGreek (Greece)Βεδακιλίνη:Susc:Pt:Απομονωμένο στέλεχος:OrdQn:MIC
Synonyms: ABXBACT MIC OrdQn Pt Susc Απομονωμένο στέλεχος Βεδακιλίνη
es-ESSpanish (Spain)Bedaquilina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (CMI)
es-MXSpanish (Mexico)Bedaquilina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (MIC)
fr-FRFrench (France)Bédaquiline:Sensibilité:Ponctuel:Isolat:Alphanumérique:CMI
it-ITItalian (Italy)Bedaquilina:Susc:Pt:Isolato:OrdQn:MIC
Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
nl-NLDutch (Netherlands)bedaquiline:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:minimaal inhiberende concentratie
Synonyms: MIC
zh-CNChinese (China)贝达喹啉:抗生素敏感性:时间点:分离株:定量型或序数型:最小抑菌浓度法
Synonyms: 6-溴-ALPHA-[2-(二甲基氨基)乙基]-2-甲氧基-ALPHA-1-萘基-BETA-苯基-3-喹啉乙醇;CAS 843663-66-1 分离物;分离菌;分离菌株;隔离种群 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 最低抑制浓度;最低抑制浓度法;最低抑菌浓度;最低抑菌浓度法;最小抑制浓度;最小抑制浓度法;最小抑菌浓度;Minimum Inhibitory Concentration;MIC

Example Units

UnitSource
ug/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88703-4