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Term Description

This term was created for the NephroCheck® test kit, which calculates the likelihood of acute kidney injury (AKI) based on urine insulin-like growth factor binding protein 7 (IGFBP-7) and tissue inhibitor of metalloproteinase 2 (TIMP-2). Both IGFBP-7 and TIMP-2 are biomarkers for AKI. Patients with a result of >0.3 have a higher risk of developing moderate or severe AKI within the subsequent 12 hours compared to those with a result of 0.3 or less. This test kit is intended to help determine the risk of AKI in conjunction with clinical evaluation for ICU patients with acute cardiovascular or respiratory compromise within the past 24 hours. PMID: 26948834

Part Description

LP266748-5   Acute kidney injury risk
Acute kidney injury (AKI), formerly known as acute renal failure, describes the rapid loss of the kidney's ability to excrete urine. Decreased urine output, elevated blood levels of the nitrogen metabolic products urea nitrogen and creatinine, and the accumulation in the blood of metabolic acids including potassium and phosphates, are symptoms of and factors used to diagnose AKI. The incidence of AKI is especially high in critically ill patients who often have comorbidities. Treatment is only supportive. The discovery of biomarkers related to AKI have sparked hope that AKI, including insulin-like growth factor binding protein 7 (IGFBP-7) and tissue inhibitor of metalloproteinase 2 (TIMP-2), may help with earlier diagnosis of AKI. PMID: 22617274 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Acute kidney injury risk:Likelihood:Pt:^Patient:Qn:Calculated.NephroCheck
Long Common Name
Acute kidney injury risk [Likelihood] by Calculated by NephroCheck
Short Name
Acute kidney injury risk NephroCheck
Display Name
Acute kidney injury risk Calculated by NephroCheck Qn
Consumer Name Alpha Get Info
Acute kidney injury risk

Part Model Get Info

  • Component
    Acute kidney injury risk
    LP266748-5
    • Analyte
      Acute kidney injury risk
      LP266748-5
      • Component Numerator
        Acute kidney injury risk
        LP266748-5
        • Component Numerator Core
          Acute kidney injury risk
          LP266748-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Likelihood
    LP185777-2
  • Time
    Pt
    LP6960-1
  • System
    ^Patient
    LP310005-6
    • System Core
      NULL
       
    • Super System
      Patient
      LP6985-8
  • Scale
    Qn
    LP7753-9
  • Method
    Calculated.NephroCheck
    LP267670-0

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.69 (MIN)
Change Reason
Release 2.69: FORMULA: Corrected formula from (|TIMP-2|*|IGFBP-7|)^2/1000 (the ^2 was incorrect).;
Order vs. Observation
Both

Formula (Readable)

(|TIMP-2|*|IGFBP-7|)/1000

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Ledviny riziko akutního poškození:Pravděpodobnost:Časový bod:^Pacient:Kvantitativní:Vypočteno pomocí testu NephroCheck
el-GRGreek (Greece)Κίνδυνος οξείας νεφρικής βλάβης:Πιθανότητα:Pt:^Ασθενής:Qn:Υπολογιζόμενο.NephroCheck
Synonyms: - CHEM Pt Qn Ασθενής Κίνδυνος οξείας νεφρικής βλάβης Πιθανότητα Υπολογιζόμενο Υπολογιζόμενο.NephroCheck
es-ESSpanish (Spain)Riesgo de lesión renal aguda:Probabilidad:Punto temporal:^paciente:Qn:Calculado por NephroCheck
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Riesgo de lesión renal aguda:Probabilidad:Punto temporal:^ Paciente:Cuantitativo:Calculado por NephroCheck
fr-FRFrench (France)Risque de lésion rénale aigûe:Probabilité:Ponctuel:^patient:Numérique:Nephrocheck calculé
it-ITItalian (Italy)Lesione renale acuta, rischio:Probabilità:Pt:^Paziente:Qn:Calcolato.NephroCheck
Synonyms: Calcolato mediante NephroCheck Chimica paziente Punto nel tempo (episodio) Rischio di lesione renale acuta
pl-PLPolish (Poland)Ryzyko ostrego uszkodzenia nerek:prawdopodobieństwo:punkt w czasie:^pacjent:ilościowy:obliczony.NephroCheck
Synonyms: Ryzyko AKI
zh-CNChinese (China)急性肾脏损伤风险:似然性:时间点:^患者:定量型:计算法.NephroCheck
Synonyms: 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 可能性;似然;可能 急性肾脏（肾）损伤风险（危险） 损伤（伤害、受伤）风险（危险性、风险性、危险） 时刻;随机;随意;瞬间 计算;计算型方法 计算型方法.NephroCheck;利用NephroCheck®检测试剂盒的计算法

Example Units

UnitSource
{risk}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88993-1