89314-9

Bacterial 23S rRNA gene azithromycin resistance mutation [Presence] by Molecular method

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Term Description

This term detects mutations in the 23S rRNA gene responsible for bacterial resistance to azithromycin.

Part Description

LP266750-1 Bacterial 23S rRNA gene azithromycin resistance mutation
Bacterial resistance to macrolide drugs has increased in conjunction with their heavy use in both medicine and animal husbandry. While there are a number of mechanisms bacteria use to resist the efficacy of drug treatment, the one used by macrolides is to bind to the large 50S subunit of the bacterial ribosome and interfere with protein synthesis. Changes of specific nucleotides in the 23S rRNA inside the large ribosomal unit are the root cause of many instances of bacterial resistance to macrolides. PMID: 11120937 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial 23S rRNA gene azithromycin resistance mutation:PrThr:Pt:Isolate/Specimen:Ord:Molgen
Long Common Name: Bacterial 23S rRNA gene azithromycin resistance mutation [Presence] by Molecular method
Short Name: Bact 23S rRNA azith res mut Islt/Spm Ql
Display Name: Bacterial 23S rRNA gene azithromycin resistance mutation Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Bacterial 23S rRNA gene azithromycin resistance mutation

Part Model Get Info

Component
Bacterial 23S rRNA gene azithromycin resistance mutation
LP266750-1
- Analyte
  Bacterial 23S rRNA gene azithromycin resistance mutation
  LP266750-1
  - Component Numerator
    Bacterial 23S rRNA gene azithromycin resistance mutation
    LP266750-1
    - Component Numerator Core
      Bacterial 23S rRNA gene azithromycin resistance mutation
      LP266750-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate/Specimen
LP266970-5
- System Core
  Isolate/Specimen
  LP266970-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Preferred Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.64
Last Updated: Version 2.65 (MAJ)
Change Reason: Updated System from "Isolate" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen 23S rRNA bakteriální rezistence na azithromycin mutace:Přítomnost nebo práh:Časový bod:Izolát/vzorek:Ordinální:Molekulární genetika
de-DE	German (Germany)	Bakterielles 23S rRNA-Gen Azithromycin-Resistenzmutation:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
el-GR	Greek (Greece)	Μετάλλαξη βακτηριακής ανθεκτικότητας του γονιδίου 23S rRNA της αζιθρομυκίνης:PrThr:Pt:Απομονωθέν στέλεχος/Δείγμα:Ord:Μοριακή γενετική Synonyms: ABXBACT Ord PrThr Pt Αζιθρομυκίνη Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Γονίδιο Δείγμα Μετάλλαξη βακτηριακής ανθεκτικότητας του γονιδίου 23S rRNA της αζιθρομυκίνης Μοριακή γενετική
es-ES	Spanish (Spain)	Mutación del Gen 23S rRNA de resistencia a azitromicina:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Mutación de resistencia a la azitromicina del gen del rRNA 23S bacteriano:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR	French (France)	Mutation gène bactérien ARNr 23S résistant à l'azithromycine:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Gene batterico 23S rRNA, mutazione resistenza a azitromicina:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Genetica molecolare Isolato o Campione Mutazione di resistenza a azitromicina di gene batterico 23S rRNA Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële azitromycineresistentie 23S-rRNA-genmutatie:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: isolaat/specimen molgen
pl-PL	Polish (Poland)	Mutacja oporności na azytromycynę w genie 23S rRNA bakterii:granica wykrywalności:punkt w czasie:szczep/izolat lub próbka:uporządkowany:genetyka molekularna Synonyms: diagnostyka molekularna Mutacja oporności na azytromycynę w bakteryjnym genie 23S rRNA
zh-CN	Chinese (China)	细菌 23S rRNA 基因阿奇霉素耐药性突变:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本核蛋白体 RNA 核蛋白体 RNA（Ribosomal RNA，RRNA）核蛋白体核糖核酸核醣体 RNA 电阻细菌 23S rRNA 基因阿奇霉素耐药性（抗性、耐性、耐药、抗药、抗药性、耐受、耐药型）突变细菌性细菌的耐性试样遗传基因;遗传因子;吉恩;生物基因阻力阿奇霉素;叠氮红霉素;西舒美;阿希红霉素;希舒美

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.