Version 2.80

Term Description

The percent of CD45RO+ cells out of the CD8 total population.

Part Descriptions

LP100021-7   Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP19063-4   Cells.CD45RO
CD45 (also known as leukocyte common antigen) is a tyrosine phosphatase specific to hematopoietic cells that is necessary for efficient T and B cell antigen receptor signal transduction. Multiple CD45 isoforms can be generated by alternative splicing of the A, B and C extracellular domains. In humans, naive T lymphocytes express CD45RA, which includes the A domain, and activated T lymphocytes express CD45RO, which does not contain A, B or C. PMID: 16423560 CD45RB and RC are not as well-understood in humans as CD45RA and RO, but peripheral T cells that express CD45RA have also been found to express high levels of CD45RB, whereas CD45RO cells do not PMID: 15020649, and high levels of CD45RC expression on CD8+ T cells may be predictive of acute kidney graft rejection in transplant patients. PMID: 23894540 Source: Regenstrief LOINC

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD45RO/Cells.CD3+CD8+
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
CD45RO cells/CD3+CD8+ (T8 suppressor cells) cells in Blood
Short Name
CD45RO Cells/CD3+CD8+ Cll NFr Bld
Display Name
CD45RO cells/CD3+CD8+ (T8 suppressor cells) cells (Bld)
Consumer Name Alpha Get Info
CD45RO cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
96493-2 T-cell naive and memory and activated subsets panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κύτταρα.CD45RO/Κύτταρα.CD3+CD8+:NFr:Pt:Αίμα:Qn:
Synonyms: CD3 CD45RO CD8 NFr Κύτταρα Κύτταρα.CD3 Κύτταρα.CD3+CD8+ Κύτταρα.CD45RO
es-ES Spanish (Spain) Células CD45RO/Células CD3+CD8+:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cells.CD45RO / 100 Cells.CD3 + CD8 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
et-EE Estonian (Estonia) Rakud.CD45RO/rakud. CD3+CD8+:NFr:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Cellules.CD45RO/Cellules.CD3+CD8+:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
fr-FR French (France) CD45RO/100 cellules CD3+CD8+:Fraction de nombres:Ponctuel:Sang:Numérique:
fr-BE French (Belgium) Cellules.CD45RO/Cellules.CD3+CD8+:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
it-IT Italian (Italy) Cellule.CD45RO/Cellule.CD3+CD8+:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD3 Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Cellule CD45RO Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) cellen.CD45RO/cellen.CD3+CD8+:getalsfractie:moment:bloed:kwantitatief:
pl-PL Polish (Poland) Komórki.CD45RO/komórki CD3+ CD8+:frakcja liczbowa:punkt w czasie:krew:ilościowy:
Synonyms: CD45RO CD8 Komórki CD45RO
ru-RU Russian (Russian Federation) Клетки.CD45RO/Клетки.CD3+CD8+:КолДоля:ТчкВрм:Кр:Колич:
Synonyms: CD3+CD8+ (T8 клетки-супрессоры) клетки Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Hücreler.CD45RO/Hücreler.CD3+CD8+:SayFr:Zmlı:Kan:Kant:
zh-CN Chinese (China) 细胞.CD45RO/细胞.CD3+CD8+:计数型分数:时间点:全血:定量型:
Synonyms: CD3+CD8+细胞 CD3细胞 CD45RO细胞 Leu2 Leu-2 Leu4;Leu-4;T3 T8 T-8 Tsuppressor UCHL-1 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89336-2