89512-8

Ganglioside GD3 IgG+IgM Ab [Presence] in Serum by Line blot

Active

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP99611-3   Ganglioside GD3
GD3 is one of the primary gangliosides found outside the central nervous system and is present in the pancreas. Approximately 50% of patients with newly diagnosed type 1 diabetes have evidence of anti-GD3 autoantibodies; however, anti-GD3 antibodies have not been found in patients with pre-diabetes, which may indicate that anti-GD3 antibodies are not a primary event in the development of diabetes. PMID: 9307889 Source: Regenstrief LOINC, PMID: 9307889

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component

Ganglioside GD3 Ab.IgG+IgM

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

Line blot

Additional Names

Short Name

GD3 Gangl IgG+IgM Ser Ql Line blot

Display Name

Ganglioside GD3 IgG+IgM Line blot Ql (S)

Consumer Name Alpha Get Info

Ganglioside GD3 IgG+IgM, Blood

Example Answer List: LL744-4

Basic Attributes

Class

SERO

Type

Laboratory

First Released

Version 2.64

Last Updated

Version 2.64

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• Disialolganglioside
• GD3 Gangl
• Immune globulin G
• Immune globulin M
• Immunoglobulin G
• Immunoglobulin M
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serology
• Serum
• SR

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LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.