LOINC
Version 2.72

89514-4Glomerular basement membrane Ab [Presence] in Serum by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP38249-6   Glomerular basement membrane Ab
Circulating glomerular basement membrane-specific antibodies are seen in Goodpasture syndrome; quantitation may be useful in monitoring treatment. This test is often used in conjunction with the antineutrophil cytoplasmic antibody (ANCA) test for Wegener granulomatosis and vasculitis. Source: LOINC partner 1

LP68423-0   Glomerular basement membrane
The layer of EXTRACELLULAR MATRIX that lies between the ENDOTHELIUM of the glomerular capillaries and the PODOCYTES of the inner or visceral layer of the BOWMAN CAPSULE. It is the product of these two cell types. It acts as a physical barrier and an ion-selective filter. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: National Library of Medicine, MeSH 2006, Basement membrane (Wikipedia)

LP68423-0   Glomerular basement membrane
The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration through the filtration slits between the podocytes, separating the blood on the inside from the filtrate on the outside. It is a fusion of the endothelial cell and podocyte basal laminas. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikepedia

Fully-Specified Name

Component
Glomerular basement membrane Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
GBM Ab Ser Ql Line blot
Display Name
Glomerular basement membrane Ab Line blot Ql (S)
Consumer Name Alpha
Glomerular basement membrane antibody, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups

LG21457-3 Glomerular basement membrane Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
肾小球基底膜 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (Netherlands)
glomerulair basaal membraan As:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (Canada)
Membrane basale glomérulaire , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
Membrane basale glomérulaire anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Membrana basale glomerulare Ab:PrThr:Pt:Siero:Ord:Line blot
es-MXSpanish (Mexico)
Membrana basal glomerular Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Membrana basal glomerular Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89514-4