Version 2.80

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.

Part Description

LP35599-7   Actin.smooth muscle
Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IgG antibodies are found in 52-85% of patients with autoimmune hepatitis (AIH) or chronic active hepatitis and in 22% of patients with primary bilary cirrhosis (PBC). Anti-actin antibodies have been reported in 3-18% of sera from normal healthy controls. Source: Quest Diagnostics Inc. , Actin (Smooth Muscle) Antibody (IgG)

Fully-Specified Name

Component
Actin.smooth muscle Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Long Common Name
Actin smooth muscle Ab [Presence] in Serum by Line blot
Short Name
SMA Ab Ser Ql Line blot
Display Name
Actin smooth muscle Ab Line blot Ql (S)
Consumer Name Alpha Get Info
Actin smooth muscle antibody, Blood

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG26320-8 Actin.smooth muscle Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ακτίνη.λείου μυός Αντίσωμα:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης
Synonyms: PrThr Ακτίνη Ακτίνη.λείου μυός Λείος μυς
es-ES Spanish (Spain) Actina de músculo liso Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX Spanish (Mexico) Actina músculo liso Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR French (France) Actine muscle lisse anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
fr-CA French (Canada) Actine.muscle lisse, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
it-IT Italian (Italy) Actina.muscolo liscio Ab:PrThr:Pt:Siero:Ord:Line blot
Synonyms: Actina muscolo liscio anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) actine.gladdespierweefsel As:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CN Chinese (China) 肌动蛋白.平滑肌 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab;自身抗体 ASMA F-actin;SMA;平滑肌肌动蛋白;平滑肌肌动蛋白（Smooth Muscle Actin，SMA） SMA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 平滑肌 Ab 平滑肌抗体（Smooth Muscle Antibodies，SMA） 平滑肌特异性;平滑肌的 平滑肌肌动蛋白 Ab 平滑肌肌动蛋白抗体 抗平滑肌抗体 抗平滑肌抗体（ASMA） 时刻;随机;随意;瞬间 线点杂交技术;线点杂交法;线条状印迹法 肌动朊;肌纤蛋白 肌动蛋白.平滑肌 Ab 肌肉 肌肉特异性 肌肉的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89520-1