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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.

Part Description

LP35599-7   Actin.smooth muscle
Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IgG antibodies are found in 52-85% of patients with autoimmune hepatitis (AIH) or chronic active hepatitis and in 22% of patients with primary bilary cirrhosis (PBC). Anti-actin antibodies have been reported in 3-18% of sera from normal healthy controls. Source: Quest Diagnostics Inc., Actin (Smooth Muscle) Antibody (IgG)

LOINC Names Get Info

Fully-Specified Name
Actin.smooth muscle Ab:PrThr:Pt:Ser:Ord:Line blot
Long Common Name
Actin smooth muscle Ab [Presence] in Serum by Line blot
Short Name
SMA Ab Ser Ql Line blot
Display Name
Actin smooth muscle Ab Line blot Ql (S)
Consumer Name Alpha Get Info
Actin smooth muscle antibody, Blood

Part Model Get Info

  • Component
    Actin.smooth muscle Ab
    LP36963-4
    • Analyte
      Actin.smooth muscle Ab
      LP36963-4
      • Component Numerator
        Actin.smooth muscle Ab
        LP36963-4
        • Component Numerator Core
          Actin.smooth muscle
          LP35599-7
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Line blot
    LP266806-1

Example Answer List: LL744-4

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
DetectedLA11882-0
Not detectedLA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG26320-8Actin.smooth muscle Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Aktin sval hladký Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
el-GRGreek (Greece)Ακτίνη.λείου μυός Αντίσωμα:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης
Synonyms: Ord PrThr Pt SERO Ακτίνη Ακτίνη.λείου μυός Αντίσωμα Γραμμή κηλίδωσης Λείος μυς Ορός
es-ESSpanish (Spain)Actina de músculo liso Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MXSpanish (Mexico)Actina músculo liso Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FRFrench (France)Actine muscle lisse Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
fr-CAFrench (Canada)Actine.muscle lisse, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
it-ITItalian (Italy)Actina.muscolo liscio Ab:PrThr:Pt:Siero:Ord:Line blot
Synonyms: Actina muscolo liscio anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)actine.gladdespierweefsel As:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CNChinese (China)肌动蛋白.平滑肌 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab;自身抗体 ASMA F-actin;SMA;平滑肌肌动蛋白;平滑肌肌动蛋白（Smooth Muscle Actin，SMA） SMA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 平滑肌 Ab 平滑肌抗体（Smooth Muscle Antibodies，SMA） 平滑肌特异性;平滑肌的 平滑肌肌动蛋白 Ab 平滑肌肌动蛋白抗体 抗平滑肌抗体 抗平滑肌抗体（ASMA） 时刻;随机;随意;瞬间 线点杂交技术;线点杂交法;线条状印迹法 肌动朊;肌纤蛋白 肌动蛋白.平滑肌 Ab 肌肉 肌肉特异性 肌肉的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89520-1