90295-7
RalA Ab [Units/volume] in Serum or Plasma by Immunoassay
Active
Part Description
LP268300-3 RalA Ab
RalA is encoded by the RalA gene and is a member of the Ras super-family of small GTPases. RalA antibody is formed in 20.1% of patients with hepatocellular carcinoma (HCC), but in much lower numbers in patients with cirrhosis (3.3%), chronic hepatitis (0%), and with no known disease (0%). Given the high RalA antibody level in response to the development of HCC, RalA antibody may be a possible tumor marker for HCC. RalA helps to sustain tumor production by regulating proliferation and survival of cells. When the expression of RalA is blocked by gene-specific silencing, the ability of human cancer cells to become malignant is greatly disrupted, if not completely prevented, which demonstrates the vital role RalA plays in Ras-induced tumorigenesis. In addition, RalA influences epidermal growth factor (EGF)-mediated cell motility that may contribute to metastasis in human cancer. PMID: 19822090
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- RalA Ab
- Property
- ACnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- RalA Ab SerPl IA-aCnc
- Display Name
- RalA Ab IA Qn
- Consumer Name Alpha Get Info
- RalA antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.68
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
90293-2 | Liver cancer antibodies and AFP panel - Serum or Plasma by Immunoassay |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Proteína RalA Anticuerpos: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | RalA Ab: |
fr-FR | French (France) | RalA anticorps: |
it-IT | Italian (Italy) | RalA Ab: Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
zh-CN | Chinese (China) | RalA 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
[arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=90295-7
LOINC Copyright
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