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Part Description

LP268293-0   Trimethylamine N-oxide
Trimethylamine N-oxide (TMAO) is a colorless amine oxide that is produced from choline, betaine, and carnitine by gut microbial metabolism. Recently, elevated plasma TMAO levels in humans have been associated with risk for serious adverse cardiovascular incidents and death. Diet, the composition of gut microbial flora, and liver flavin monooxygenase activity all affect the plasma levels of TMAO. Foods that contain choline, lecithin, and carnitine, including red meat, eggs, dairy products, and salt-water fish, are sources of TMAO. TMAO alters cholesterol and bile metabolism, activates inflammatory pathways, and promotes foam cell formation. It is strongly suspected in mediating the development of type-2 diabetes mellitus. TMAO also increases with decreasing kidney function, and is associated with an increased risk of death in patients with chronic kidney disease. Treatments being explored to lower TMAO include broad-spectrum antibiotics to eliminate TMAO producing bacteria, the promotion of the growth of bacteria that utilize TMAO as a substrate, and the development of target-specific molecules. PMID: 27834801 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Trimethylamine N-oxide:SCnc:Pt:Ser/Plas:Qn:LC/MS/MS
Long Common Name
Trimethylamine N-oxide [Moles/volume] in Serum or Plasma by LC/MS/MS
Short Name
TMAO SerPl LC/MS/MS-sCnc
Display Name
Trimethylamine N-oxide LC/MS/MS [Moles/Vol]
Consumer Name Alpha Get Info
Trimethylamine n-oxide, Blood

Part Model Get Info

  • Component
    Trimethylamine N-oxide
    LP268293-0
    • Analyte
      Trimethylamine N-oxide
      LP268293-0
      • Component Numerator
        Trimethylamine N-oxide
        LP268293-0
        • Component Numerator Core
          Trimethylamine N-oxide
          LP268293-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    LC/MS/MS
    LP95062-3

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Trimethylamin N-oxid:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:Kapalinová chromatografie s tandemovou hmotnostní spektrometrií (LC/MS/MS)
el-GRGreek (Greece)Ν-οξείδιο της τριμεθυλαμίνης:SCnc:Pt:Ορός/Πλάσμα:Qn:LC/MS/MS
Synonyms: CHEM LC/MS/MS N Pt Qn SCnc Ν-οξείδιο της τριμεθυλαμίνης Ορός Ορός/Πλάσμα Πλάσμα Τριμεθυλαμίνη
es-ESSpanish (Spain)N-óxido de trimetilamina:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:LC/MS/MS
Synonyms: Cuantitativo
es-MXSpanish (Mexico)N-óxido de trimetilamina:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:LC / MS / MS
fr-FRFrench (France)Triméthylamine N-oxyde:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:LC/MS/MS
it-ITItalian (Italy)Trimetilammina N-ossido:SCnc:Pt:Siero/Plasma:Qn:LC/MS/MS
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
zh-CNChinese (China)三甲基胺 N-氧化物:物质的量浓度:时间点:血清/血浆:定量型:LC/MS/MS
Synonyms: N 型 Tandem Mass Spectrometry;MS/MS;串联质谱分析;串联质谱法;mass spectrometer;MS;质谱法;质谱分析;liquid chromatography;LC;液相色谱分析;Liquid Chromatography-Tandem Mass Spectrometry;liquid chromatography-MS/MS;LC-MS/MS;液相色谱分析-串联质谱分析法;液相色谱-串联质谱检测方法;液相色谱质谱联用技术;串联质谱快速分析 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 氧化三甲胺;氧化三甲胺;三甲基胺N氧化物;CAS 62637-93-8 血清或血浆

Example Units

UnitSource
umol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90360-9