Version 2.78

Part Description

LP268293-0   Trimethylamine N-oxide
Trimethylamine N-oxide (TMAO) is a colorless amine oxide that is produced from choline, betaine, and carnitine by gut microbial metabolism. Recently, elevated plasma TMAO levels in humans have been associated with risk for serious adverse cardiovascular incidents and death. Diet, the composition of gut microbial flora, and liver flavin monooxygenase activity all affect the plasma levels of TMAO. Foods that contain choline, lecithin, and carnitine, including red meat, eggs, dairy products, and salt-water fish, are sources of TMAO. TMAO alters cholesterol and bile metabolism, activates inflammatory pathways, and promotes foam cell formation. It is strongly suspected in mediating the development of type-2 diabetes mellitus. TMAO also increases with decreasing kidney function, and is associated with an increased risk of death in patients with chronic kidney disease. Treatments being explored to lower TMAO include broad-spectrum antibiotics to eliminate TMAO producing bacteria, the promotion of the growth of bacteria that utilize TMAO as a substrate, and the development of target-specific molecules. PMID: 27834801 Source: Regenstrief LOINC

Fully-Specified Name

Component
Trimethylamine N-oxide
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
LC/MS/MS

Additional Names

Short Name
TMAO SerPl LC/MS/MS-sCnc
Display Name
Trimethylamine N-oxide LC/MS/MS [Moles/Vol]
Consumer Name Alpha Get Info
Trimethylamine n-oxide, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) N-óxido de trimetilamina:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:LC/MS/MS
Synonyms: Cuantitativo
es-MX Spanish (Mexico) N-óxido de trimetilamina:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:LC / MS / MS
fr-FR French (France) Triméthylamine N-oxyde:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:LC/MS/MS
it-IT Italian (Italy) Trimetilammina N-ossido:SCnc:Pt:Siero/Plasma:Qn:LC/MS/MS
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
zh-CN Chinese (China) 三甲基胺 N-氧化物:物质的量浓度:时间点:血清/血浆:定量型:LC/MS/MS
Synonyms: N 型 Tandem Mass Spectrometry;MS/MS;串联质谱分析;串联质谱法;mass spectrometer;MS;质谱法;质谱分析;liquid chromatography;LC;液相色谱分析;Liquid Chromatography-Tandem Mass Spectrometry;liquid chromatography-MS/MS;LC-MS/MS;液相色谱分析-串联质谱分析法;液相色谱-串联质谱检测方法;液相色谱质谱联用技术;串联质谱快速分析 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 氧化三甲胺;氧化三甲胺;三甲基胺N氧化物;CAS 62637-93-8 血清或血浆

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90360-9