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Term Description

This panel is used to evaluate patients who have clinical features associated with IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked inheritance) and primary immunodeficiencies, autoimmune disease, allergy and asthma, and graft-vs-host disease after hematopoietic stem cell transplantation.

Part Description

LP268346-6   T-cell regulatory subsets panel
Regulatory T-cells (Tregs) are a subset of CD4+ T-cells that provide protection from excess inflammation and tissue damage that would result from untethered immune responses directed against self, dietary, or environmental antigens. Tregs are characterized and dependent upon the expression of lineage-specific transcription factor Foxp3 and high levels of interleukin-2 (IL2) receptor alpha-chain (CD25). Tregs require the expression of CD25 for their differentiation and proliferative fitness and are dependent on IL2 signaling for their maintenance. Tregs suppress immune-mediated inflammation that is associated with autoimmune and auto-inflammatory disorders, allergies, acute and chronic infections, and cancer. Associations of Tregs with disease has prompted investigations into the manipulation of Tregs for therapeutic purposes. PMID: 27590281 Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINCNameR/O/CCardinalityExample UCUM Units
90413-6T-cell regulatory (Treg) subsets panel - Blood
Indent26982-9CD4+CD25+ cells [#/volume] in Blood/uL
Indent13332-2CD4+CD25+ cells/cells in Blood%
Indent89315-6CD4+CD25+CD45RA+CD127Low+ cells [#/volume] in Blood{cells}/uL
Indent89316-4CD4+CD25+CD45RO+CD127Low+ cells [#/volume] in Blood{cells}/uL
Indent89317-2CD4+CD25-CD127+ cells [#/volume] in Blood{cells}/uL
Indent89319-8CD25+CD45RA+CD127Low+ cells/CD4 cells in Blood%
Indent89320-6CD25+CD45RO+CD127Low+ cells/CD4 cells in Blood%
Indent89318-0CD25-CD127+ cells/CD4 cells in Blood%

LOINC Names Get Info

Fully-Specified Name
T-cell regulatory subsets panel:-:Pt:Bld:-:
Long Common Name
T-cell regulatory (Treg) subsets panel - Blood
Short Name
T-cell regulatory subsets Pnl Bld
Display Name
T-cell regulatory (Treg) subsets panel (Bld)
Consumer Name Alpha Get Info
T-cell Regulatory (Treg) Subsets Panel, Blood

Part Model Get Info

  • Component
    T-cell regulatory subsets panel
    LP268346-6
    • Analyte
      T-cell regulatory subsets panel
      LP268346-6
      • Component Numerator
        T-cell regulatory subsets panel
        LP268346-6
        • Component Numerator Core
          T-cell regulatory subsets panel
          LP268346-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    -
    LP6769-6
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
PANEL.CELLMARK
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65 (ADD)
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)T buňky regulační (Treg) subpopulace panel:-:Časový bod:Krev:-:
el-GRGreek (Greece)Πίνακας υποομάδας ρυθμιστικών Τ-κυττάρων:-:Pt:Αίμα:-:
Synonyms: - CELLMARK PANEL.CELLMARK Pt Αίμα Πίνακας υποομάδας ρυθμιστικών Τ-κυττάρων Τ-κύτταρο
es-MXSpanish (Mexico)Panel de subconjuntos reguladores de células T:-:Punto temporal:Sangre:-:
es-ESSpanish (Spain)Panel de subclases de Células T reguladoras:Propiedades mixtas (sólo paneles):Punto temporal:Sangre:-:
fr-FRFrench (France)Sous-populations lymphocytaires T régulatrices panel:-:Ponctuel:Sang:-:
it-ITItalian (Italy)Linfocita T regolatore, subset panel:-:Pt:Sangue:-:
Synonyms: Linfocita T Modelli di superficie cellulare Panel subset linfocita T regolatore (Treg) Punto nel tempo (episodio) Sangue Set di prescrizione per marcatore cellulare
zh-CNChinese (China)T-细胞调节亚群组套:-:时间点:全血:-:
Synonyms: T 细胞;UCHL-1 T-细胞（T细胞）调节亚群（子群、子集）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.细胞标志物;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.细胞标志物;实验室医嘱组类.细胞标志物;细胞标志物医嘱组;细胞标志物医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 细胞标志物 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90413-6
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/90413-6