Version 2.78

Part Descriptions

LP173437-7   O-nortramadol
O-desmethyltramadol (M1) is an active metabolite of tramadol which is a narcotic analgesic used to treat severe pain. [PubChem: Tramadol] Tramadol and M1 work synergistically to relieve pain. M1 activates the opioid receptor responsible for the analgesic effect of tramadol. The parent drug prevents reuptake of norepinephrine and serotonin which inhibits pain signal transmission in the spinal cord. M1 metabolism is highly dependent upon CYP2D6 which influences the efficacy of pain relief experienced by the patient. The predominant adverse side effects associated with tramadol use include nausea, vomiting, sweating, itching, constipation, headache and central nervous system stimulation.(http://boris.unibe.ch/69119/1/01213011-201407000-00007.pdf) Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component
O-Nortramadol
Property
MCnc
Time
Pt
System
Saliva
Scale
Qn
Method
Confirm

Additional Names

Short Name
O-nortramadol Sal Cfm-mCnc
Display Name
O-nortramadol Confirm (Sal) [Mass/Vol]
Consumer Name Alpha Get Info
O-nortramadol, Saliva

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG37717-2 O-nortramadol|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) O-Desmetiltramadol:Concentración de masa:Punto temporal:Saliva:Qn:Confirmatorio
Synonyms: Cuantitativo
es-MX Spanish (Mexico) O-nortramadol:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Confirmar
fr-FR French (France) O-nortramadol:Masse/Volume:Ponctuel:Salive:Numérique:Confirmation
it-IT Italian (Italy) O-nortramadolo:MCnc:Pt:Saliva:Qn:Conferma
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) O-desmethyltramadol:massa/volume:moment:speeksel:kwantitatief:bevestiging
ru-RU Russian (Russian Federation) O-дезметилтрамадол:МассКонц:ТчкВрм:Слюна:Колич:Подтверждать
Synonyms: Количественный Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) O-dezmetiltramadol:KütlKons:Zmlı:Tükürük:Kant:Onay
Synonyms: Teyid
zh-CN Chinese (China) O-去甲基曲马多:质量浓度:时间点:唾液:定量型:毒理学确认试验
Synonyms: O-去甲曲马多;曲马多代谢产物;曲马多代谢物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 津;津液;涎 确认方法;确认法;确认试验 脱甲基曲马多;曲马多代谢产物;曲马多代谢物 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90750-1