Version 2.78

Part Descriptions

LP30843-4   Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein. Source: Regenstrief LOINC

LP37039-2   Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor. Source: ARUP Laboratories

LP37039-2   Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system. Source: Regenstrief LOINC

Fully-Specified Name

Component
Amphiphysin Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
Amphiphysin Ab CSF Ql IF
Display Name
Amphiphysin Ab IF Ql (CSF)
Consumer Name Alpha Get Info
Amphiphysin antibody, Spinal fluid

Example Answer List: LL2038-9

Source: Quest Diagnostics Inc.
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) LA11884-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94818-2 Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence

Member of these Groups Get Info

LOINC Group Group Name
LG24036-2 Amphiphysin Ab|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Anfifisina Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Amphiphysin Ab:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Amfifüsiin antikehad:PrThr:Pt:CSF:Ord:IF
Synonyms: Järgarvuline Juhuslik Liikvor
fr-FR French (France) Amphiphysine anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Amphiphysine Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunofluorescence
Synonyms: Anticorps
fr-CA French (Canada) Amphiphysine, Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunofluorescence
it-IT Italian (Italy) Amfifisina Ab:PrThr:Pt:LCS:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) amfifysine As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
ru-RU Russian (Russian Federation) Амфифизин Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Amfifizin Ab:MevcEşik:Zmlı:BOS:Srl:IF
Synonyms: Ak İmmünflorerans Mevcut
zh-CN Chinese (China) 双载蛋白 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ab;自身抗体 Amphiphysin Ab CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 两亲蛋白;两性蛋白;Amphiphysin（一种位于神经元突触前膜的 128kD 蛋白）;神经元突触囊泡 Amphiphysin;两性蛋白(僵直人综合征伴乳腺癌128kDa 自身抗原);amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90815-2