90816-0
Amphiphysin Ab [Units/volume] in Cerebrospinal Fluid by Line blot
Active
Part Descriptions
LP30843-4 Amphiphysin
Amphiphysin is a protein associated with the cytoplasmic surface of synaptic vesicles and is encoded by the AMPH gene. Patients with stiff man syndrome and breast cancer can be positive with autoantibodies against the amphiphysin protein.
Source: Regenstrief LOINC
LP37039-2 Amphiphysin Ab
Paraneoplastic syndromes (PNS) are diseases associated with remote effects of tumors, of which small-cell lung cancer (SCLC), ovarian cancer, breast cancer, thymoma, Hodgkin lymphoma, and testicular cancer are the most common. Stiff-person syndrome (SPS) is a rare neurological disorder characterized by stiffness of skeletal muscles with superimposed spasms, which can have an idiopathic or paraneoplastic component. First described in women with breast cancer and SPS, amphiphysin antibodies have been reported in patients with diverse paraneoplastic neurological disorders, and cancers. Amphiphysin antibodies are considered diagnosic for paraneoplastic neurologic syndromes and can direct the search for an occult tumor, recurrence of tumor, or second tumor.
Source: ARUP Laboratories
LP37039-2 Amphiphysin Ab
Amphiphysin is a brain-enriched protein normally found only within the membrane of synaptic vesicles in neural tissue. Antibodies against amphiphysin (128kDa) are directed against the protein amphiphysin, and their presence plays an important diagnostic role in paraneoplastic syndromes (e.g. Lambert Eaton myasthenia syndrome, encephalomyelitis with rigidity, cerebellar syndrome, sensory neuronopathy, opsoclonus myoclonus ataxia, and Stiff-man syndrome). Paraneoplastic syndromes are autoantibody-mediated neurologic disorders most commonly associated with cancers of the lung, breast, ovaries or lymphatic system.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Amphiphysin Ab:
ACnc: Pt: CSF: Qn: Line blot - Long Common Name
- Amphiphysin Ab [Units/volume] in Cerebrospinal Fluid by Line blot
- Short Name
- Amphiphysin Ab CSF Line blot-aCnc
- Display Name
- Amphiphysin Ab Line blot Qn (CSF)
- Consumer Name Alpha Get Info
- Amphiphysin antibody, Spinal fluid
Part Model Get Info
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.83 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Amfifysin Ab: |
| el-GR | Greek (Greece) | Αμφιφυσίνη Αντίσωμα: Synonyms: ACnc Pt Qn SERO Αμφιφυσίνη Αντίσωμα Γραμμή κηλίδωσης ΕΝΥ |
| es-ES | Spanish (Spain) | Anfifisina Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Amphiphysin Ab: |
| fr-FR | French (France) | Amphiphysine Ac: |
| fr-CA | French (Canada) | Amphiphysine, Ac: |
| it-IT | Italian (Italy) | Amfifisina Ab: Synonyms: anticorpo Concentrazione Arbitraria Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | amfifysine As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Amfifizyna Ab: Synonyms: Przeciwciała do amfifizyny |
| zh-CN | Chinese (China) | 双载蛋白 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/L | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://