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Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Neuronal nuclear type 3 Ab:Titr:Pt:CSF:SemiQn:IF
Long Common Name
Neuronal nuclear type 3 Ab [Titer] in Cerebrospinal Fluid by Immunofluorescence
Short Name
Hu3 Ab Titr CSF IF
Display Name
Neuronal nuclear type 3 Ab IF (CSF) [Titer]
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Spinal fluid

Part Model Get Info

  • Component
    Neuronal nuclear type 3 Ab
    LP39196-8
    • Analyte
      Neuronal nuclear type 3 Ab
      LP39196-8
      • Component Numerator
        Neuronal nuclear type 3 Ab
        LP39196-8
        • Component Numerator Core
          Neuronal nuclear type 3
          LP31707-0
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    IF
    LP6323-2

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
94818-2Paraneoplastic Ab panel - Cerebrospinal Fluid by Immunofluorescence

Member of these Groups Get Info

LOINC GroupGroup Name
LG50122-7Neuronal nuclear type 3 Ab|Titr|Pt|CSF

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Antinukleární protilátky typu 3 neuronální:Arbitrární koncentrace (titr):Časový bod:Mozkomíšní mok:Semikvantitativní:Imunofluoresecence (IF)
el-GRGreek (Greece)Νευρωνικός πυρηνικός τύπος 3 Αντίσωμα:Titr:Pt:ΕΝΥ:Ημιποσοτική:Ανοσοφθορισμός
Synonyms: Pt SERO Titr Type Ανοσοφθορισμός Αντίσωμα ΕΝΥ Ημιποσοτική Νευρωνικό Νευρωνικό πυρηνικό Νευρωνικός πυρηνικός τύπος 3 Πυρηνικό
es-ESSpanish (Spain)Neuronal nuclear tipo 3 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Tipo nuclear neuronal 3 Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunofluorescencia (IF)
fr-FRFrench (France)Neurone noyau type 3 Ac:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:Immunofluorescence
fr-CAFrench (Canada)Neuronal nucléaire de type 3, Ac:Titre:Temps ponctuel:LCR:SemiQn:Immunofluorescence
it-ITItalian (Italy)Nucleare neuronale tipo 3 Ab:Titr:Pt:LCS:SemiQn:IF
Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NLDutch (Netherlands)neuronaal nucleair type 3 As:titer:moment:liquor cerebrospinalis:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF soort
pl-PLPolish (Poland)Typ 3 neuronalny jądrowy Ab:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
zh-CNChinese (China)神经元细胞核 3 型 抗体:滴定度:时间点:脑脊液:半定量型:免疫荧光法
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 FANA Hu3 Ab Hu3 抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 III 三 叁 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 核心抗原抗体免疫荧光 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90837-6