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Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Neuronal nuclear type 3 Ab:ACnc:Pt:CSF:Qn:Line blot
Long Common Name
Neuronal nuclear type 3 Ab [Units/volume] in Cerebrospinal Fluid by Line blot
Short Name
Hu3 Ab CSF Line blot-aCnc
Display Name
Neuronal nuclear type 3 Ab Line blot Qn (CSF)
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Spinal fluid

Part Model Get Info

  • Component
    Neuronal nuclear type 3 Ab
    LP39196-8
    • Analyte
      Neuronal nuclear type 3 Ab
      LP39196-8
      • Component Numerator
        Neuronal nuclear type 3 Ab
        LP39196-8
        • Component Numerator Core
          Neuronal nuclear type 3
          LP31707-0
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Line blot
    LP266806-1

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Antinukleární protilátky typu 3 neuronální:Arbitrární koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:Line blot
el-GRGreek (Greece)Νευρωνικός πυρηνικός τύπος 3 Αντίσωμα:ACnc:Pt:ΕΝΥ:Qn:Γραμμή κηλίδωσης
Synonyms: ACnc Pt Qn SERO Type Αντίσωμα Γραμμή κηλίδωσης ΕΝΥ Νευρωνικό Νευρωνικό πυρηνικό Νευρωνικός πυρηνικός τύπος 3 Πυρηνικό
es-ESSpanish (Spain)Neuronal nuclear tipo 3 Anticuerpos:Concentración arbitraria:Punto temporal:Líquido Cefalorraquideo:Qn:Line blot
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Tipo nuclear neuronal 3 Ab:Concentración arbitraria:Punto temporal:Fluído espinal cerebral:Cuantitativo:Mancha de línea
fr-FRFrench (France)Neurone noyau type 3 Ac:Arbitraire/Volume:Ponctuel:Liquide céphalorachidien:Numérique:Blot en ligne
fr-CAFrench (Canada)Neuronal nucléaire de type 3, Ac:Concentration arbitraire:Temps ponctuel:LCR:Quantitatif:Immunoessai sur bandelette
it-ITItalian (Italy)Nucleare neuronale tipo 3 Ab:ACnc:Pt:LCS:Qn:Line blot
Synonyms: anticorpo Concentrazione Arbitraria Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)neuronaal nucleair type 3 As:eenheid/volume:moment:liquor cerebrospinalis:kwantitatief:lijnblot
Synonyms: antistof; antilichaam soort
pl-PLPolish (Poland)Typ 3 neuronalny jądrowy Ab:stężenie w jednostkach umownych:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:line blot
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
zh-CNChinese (China)神经元细胞核 3 型 抗体:任意型浓度:时间点:脑脊液:定量型:线点印迹法
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Hu3 Ab Hu3 抗体 III 三 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 型 时刻;随机;随意;瞬间 核;胞核 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 线点杂交技术;线点杂交法;线条状印迹法 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
[arb'U]/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90838-4