90908-5

Eicosapentaenoate (C20:5w3)+Docosapentaenate (C22:5w3)+Docosahexaenoate (C22:6w3)/Fatty acids.C14-C22 risk [Interpretation] in Blood Qualitative

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Term Description

Risk of sudden death due to cardiovascular disease based on the % of EPA+DPA+DHA out of total fatty acids C14-C22. This term was created for, but is not limited in use to, the submitter's OmegaCheck test performed at the Cleveland Heart Lab. Note that a similar LOINC exists for the risk of cardiovascular disease based on % of EPA+DHA out of total fatty acids C14-C24 [LOINC: 88999-8].
Source: Regenstrief LOINC

Part Descriptions

LP269615-3 Eicosapentaenoate+Docosapentaenate w3+Docosahexaenoate
Docosapentaenoic acid designates any straight chain 22:5 fatty acid. Two isomers are of particular interest

all-cis-7,10,13,16,19-docosapentaenoic acid is an ω-3 fatty acid with the trivial name clupanodonic acid, commonly called DPA. It is an intermediary between eicosapentaenoic acid (EPA, 20:5 ω-3) and docosahexaenoic acid (DHA, 22:6 ω-3). Seal oil is a rich source.

all-cis-4,7,10,13,16-docosapentaenoic acid is an ω-6 fatty acid with the trivial name Osbond acid. It is formed by an elongation and desaturation of arachidonic acid 20:4 ω-6. In mammals, clupanodonic acid deficiency is accompanied by an increase of this isomer; the Osbond/DHA ratio is thus a marker of dietary DHA sufficiency Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP269615-3 Eicosapentaenoate+Docosapentaenate w3+Docosahexaenoate
Eicosapentaenoate (EPA) is a long chain omega-3 fatty acid that is present throughout the body including in cell membranes. EPA is found in fatty fish including salmon, tuna, mackerel, sardines, shellfish, and herring. EPA can be biosynthesized from alpha-linolenic acid (ALA), but it is much more efficient to increase levels by including EPA-rich sources in one's diet. EPA has anti-inflammatory properties that are vital to fetal development and the process of healthy aging. Its anti-inflammatory effects are due to reduced gene expression of genes involved in inflammatory and atherogenesis-related pathways, thereby lowering the risk of cardiovascular disease. EPA has also been found to increase platelet stability, decrease endothelial activation, and improve vascular permeability. Taking EPA supplements leads to an increased amount of EPA in the plaque of carotid arteries which may decrease inflammation and increase plaque stability. PMID: 22332096 Many other studies have been run that show acorrelation between higher plasma levels of EPA and reduced symptoms of disease, some of which include Alzheimer's disease, depression, rheumatoid arthritis, and Raynaud Syndrome.[ http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000301] Source: Regenstrief LOINC

LP269615-3 Eicosapentaenoate+Docosapentaenate w3+Docosahexaenoate
Docosahexaenoate (DHA) is one of the essential polyunsaturated omega-3 fatty acids that is primarily obtained by ingesting fatty fish including salmon, mackerel, tuna, herring, and sardines.[https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/] There are many benefits derived from eating healthy levels of DHA including a reduction of chronic inflammation, atherosclerosis, hypertension, arthritis, depression, adult-onset diabetes mellitus, myocardial infarction, thrombosis, and some cancers. DHA is important in brain development of infants and in maintaining normal brain function in adults. Studies have demonstrated that infants who drink DHA-fortified formula have higher visual acuity than infants who drink unfortified formula. Deficiencies of DHA have been associated with fetal alcohol syndrome, attention deficit hyperactivity disorder, cystic fibrosis, phenylketonuria, unipolar depression, aggressive hostility, adrenoleukodystrophy, cognitive decline in aging individuals, and the onset of sporadic Alzheimer's disease. Patients who consume 200 mg/day of DHA have a 50% reduction in the incidence of sudden cardiac arrest. PMID: 10479465 Source: Regenstrief LOINC

Fully-Specified Name

Component: Eicosapentaenoate+Docosapentaenate w3+Docosahexaenoate/Fatty acids.C14-C22 risk
Property: Imp
Time: Pt
System: Bld
Scale: Ord
Method

Additional Names

Short Name: EPA+DPA+DHA/FA.C14-C22 risk Bld Imp
Display Name: EPA+DPA+DHA/Fatty acids.C14-C22 risk Ql (Bld) [Interp]
Consumer Name Alpha Get Info: EPA+DPA+DHA/Fatty Acids.C14-C22 Risk, Blood

Preferred Answer List: LL5181-4

Source: Cleveland Heart Lab

Answer	Code	Score	Answer ID
High risk High risk of sudden death due to cardiovascular disease based on (EPA+DPA+DHA/Fatty acids.C14-C22) <= 3.7 %			LA19541-4
Moderate risk Moderate risk of sudden death due to cardiovascular disease based on (EPA+DPA+DHA/Fatty acids.C14-C22) between 3.8 and 5.5 %			LA29616-2
Low risk Low risk of sudden death due to cardiovascular disease based on (EPA+DPA+DHA/Fatty acids.C14-C22) >= 5.5%			LA19542-2

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.65
Last Updated: Version 2.65
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
90918-4	Fatty acid omega-3 and omega-6 panel - Blood

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Eicosapentaenoico + Docosapentaenoico w3 + Docosahexaenoico/Riesgo por ácidos grasos C14-C22:Impresión/interpretación del estudio:Punto temporal:Sangre:Ord:
es-MX	Spanish (Mexico)	Eicosapentaenoato + Docosapentaenato w3 + Docosahexaenoato / Ácidos grasos Riesgo C14-C22:Impresión / interpretación del estudio:Punto temporal:Sangre:Ordinal:
fr-FR	French (France)	Eicosapentaénoate+docosapentaénate w3+Docosahexaénoate/acides gras C14-C22 risque:Interprétation:Ponctuel:Sang:Qualitatif:
it-IT	Italian (Italy)	Eicosapentaenoato+Docosapentaenate w3+Docosaesaenoato/Acidi grassi.C14-C22, rischio:Imp:Pt:Sangue:Ord: Synonyms: Chimica Docosaesaenoato (C22:6w3) Docosapentaenate (C22:5w3) Eicosapentaenoato (C20:5w3) Impressione/interpretazione di studio Punto nel tempo (episodio) Sangue
zh-CN	Chinese (China)	二十碳五烯酸+二十二碳五烯酸 w3+二十二碳六烯酸/脂肪酸类.C14-C22 风险:印象:时间点:全血:序数型: Synonyms: C20:5w3;EPA;二十碳五烯酸（Eicosapentaenoic acid，EPA）;二十碳五烯酸, C20:5w3;二十碳双烯酸;附子脂酸;附子脂酸, C20:5w3 C22:5w3;DPA;二十二碳五烯酸;二十二碳五烯酸（Docosapentaenic acid，DPA）;二十二碳五烯酸, C22:5w3 C22:6w3;DHA;二十二碳六烯酸（Docosahexaenoic acid，DHA）;二十二碳六烯酸, C22:6w3;二十二碳六烯酸 w3 二十碳五烯酸（二十碳五烯酸酯或盐）+二十二碳五烯酸 w3（C22:5w3、DPA、二十二碳五烯酸、二十二碳五烯酸, C22:5w3）+二十二碳六烯酸（DHA、C22:6w3、二十二碳六烯酸 w3）依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释时刻;随机;随意;瞬间类脂化合物;类脂物;脂类;脂肪酸;脂质脂肪酸.C14-C22 风险血;血液

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.