91065-3
14-3-3 protein [Presence] in Tissue by NAA with probe detection
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Part Descriptions
LP33554-4 14-3-3 protein
14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. The 14-3-3 proteins eluted in the 14th fraction of bovine brain homogenate and were found on positions 3.3 of subsequent electrophoresis by Moore and Perez. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
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Source: Wikipedia, Wikipedia
LP33554-4 14-3-3 protein
The 14-3-3 protein is a highly conserved family of proteins that was originally found in brain tissue in 1968. There are seven isoforms of 14-3-3 protein in mammals which are found in all eukaryotic cells. The proteins weigh between 25 and 30 kilo Daltons and interact with more than 200 target proteins. 14-3-3 proteins are able to easily move between the cytoplasm and the nucleus but are mainly found in the cytoplasm. 14-3-3 is an important regulator of cellular function including controlling the cycle of the cell, cell growth, differentiation, survival, apoptosis, migration and spreading. The isoform 14-3-3o is believed to have a role in human cancer development. PMID: 15857577
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 14-3-3 protein
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- 14-3-3 protein Tiss Ql NAA+probe
- Display Name
- 14-3-3 protein NAA+probe Ql (Tiss)
- Consumer Name Alpha Get Info
- 14-3-3 protein, Tissue
Example Answer List: LL1937-3
Source: 3M Health Information Systems| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | 14-3-3 Protein: |
| es-ES | Spanish (Spain) | Proteína 14-3-3: |
| es-MX | Spanish (Mexico) | Proteína 14-3-3: |
| fr-BE | French (Belgium) | Protéine 14-3-3: |
| fr-CA | French (Canada) | Protéine 14-3-3: |
| fr-FR | French (France) | Protéine 14-3-3: |
| it-IT | Italian (Italy) | 14-3-3, proteina: Synonyms: Presenza o Soglia Proteina 14-3-3 Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tessuto & |
| nl-NL | Dutch (Netherlands) | 14-3-3 eiwit: Synonyms: probe.amp.tar |
| ru-RU | Russian (Russian Federation) | 14-3-3 протеин: Synonyms: 14-3-3 белок Белок ДНК проба; |
| tr-TR | Turkish (Turkey) | 14-3-3 protein: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 14-3-3 蛋白: Synonyms: Ⅲ Creutzfeldt-Jacob 病; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=91065-3
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