Version 2.77

Part Descriptions

LP33554-4   14-3-3 protein
14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. The 14-3-3 proteins eluted in the 14th fraction of bovine brain homogenate and were found on positions 3.3 of subsequent electrophoresis by Moore and Perez. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Wikipedia

LP33554-4   14-3-3 protein
The 14-3-3 protein is a highly conserved family of proteins that was originally found in brain tissue in 1968. There are seven isoforms of 14-3-3 protein in mammals which are found in all eukaryotic cells. The proteins weigh between 25 and 30 kilo Daltons and interact with more than 200 target proteins. 14-3-3 proteins are able to easily move between the cytoplasm and the nucleus but are mainly found in the cytoplasm. 14-3-3 is an important regulator of cellular function including controlling the cycle of the cell, cell growth, differentiation, survival, apoptosis, migration and spreading. The isoform 14-3-3o is believed to have a role in human cancer development. PMID: 15857577 Source: Regenstrief LOINC

Fully-Specified Name

14-3-3 protein

Additional Names

Short Name
14-3-3 protein Tiss Ql NAA+probe
Display Name
14-3-3 protein NAA+probe Ql (Tiss)
Consumer Name Alpha Get Info
14-3-3 protein, Tissue

Example Answer List: LL1937-3

Source: 3M Health Information Systems
Answer Code Score Answer ID
PresentCopyright ID:52101004 Present (qualifier value) LA9633-4
AbsentCopyright ID:2667000 Absent (qualifier value) LA9634-2

Basic Attributes

First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) 14-3-3 Protein:Nachweis oder Schwellenwert:Zeitpunkt:Gewebe:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Proteína 14-3-3:PrThr:Punto temporal:Tejido:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Proteína 14-3-3:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-BE French (Belgium) Protéine 14-3-3:PrThr:Temps ponctuel:Tissu:Ordinal:Sonde avec amplification de la cible
fr-CA French (Canada) Protéine 14-3-3:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Protéine 14-3-3:Présence/Seuil:Ponctuel:Tissu:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) 14-3-3, proteina:PrThr:Pt:Tessuto:Ord:Sonda.amp.tar
Synonyms: Presenza o Soglia Proteina 14-3-3 Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Tessuto & Strisci
nl-NL Dutch (Netherlands) 14-3-3 eiwit:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:probe-detectie
Synonyms: probe.amp.tar
ru-RU Russian (Russian Federation) 14-3-3 протеин:PrThr:ТчкВрм:Тк:Пор:Проба.усил.миш
Synonyms: 14-3-3 белок Белок ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) 14-3-3 protein:MevcEşik:Zmlı:Doku:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 14-3-3 蛋白:存在情况或阈值:时间点:组织与涂片:序数型:探针法.基因扩增.靶向
Synonyms: Ⅲ Creutzfeldt-Jacob 病;Creutzfeldt-Jakob 病;人克-雅氏病;人类克雅二氏症;人类型狂牛症;人类库贾氏病;人类朊蛋白病;克一维二氏病;克-雅氏病;克-雅病;库贾氏病 III PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 三 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 经过扩增的 脱氧核糖核酸探针 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

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