91078-6
Zika virus RNA [Presence] in Blood by NAA with probe detection
Active
Term Description
Zika virus RNA may be detected in whole blood specimens for a longer time period after symptom onset compared to serum or plasma, and the detection rate for whole blood is similar to that in urine specimens 10 or more days after symptom onset. In contrast, the virus is detectable earlier in serum or plasma specimens compared to whole blood. A longer period of detection in whole blood has also been reported for other Flaviviruses including West Nile virus and Dengue virus. PMID: 28648495
Source: Regenstrief LOINC
Part Descriptions
LP200137-0 Zika virus
Zika virus (ZIKV) is a flavivirus transmitted primarily by the Aedes mosquito which was first identified in a sentinel monkey in the Zika forest in Uganda in 1947. Since 2014 it has spread explosively in the Americas where it has infected hundreds of thousands of people. About 80% of those infected are asymptomatic. Common symptoms include fever, headache, rash, arthralgia and conjunctivitis. Since the end of 2015, there has been an increase in ZIKV-associated cases of Guillain-Barre syndrome and a tremendous increase in cases of microcephaly in fetuses and newborns in Brazil, raising worldwide public health concern. Recent predictions are that the mosquito species A. Albopictus, which can hibernate and survive cool temperatures, will carry ZIKV to more temperate areas of North America, Australia and Southern Europe. It is still not clear whether ZIKV in humans increases viral titers enough to trigger a new cycle when an infected person is bitten by a naïve mosquito. Direct human-to-human transmission has been documented to occur perinatally, sexually (primarily through semen), through breastfeeding, blood transfusion and through occupational transmission in the laboratory setting. There are currently no specific anti-viral agents, vaccination or medical prophylaxis available. PMID: 27148186
Source: Regenstrief LOINC
LP203271-4 Zika virus RNA
Zika virus contains an inner nucleocapsid composed of RNA and multiple copies of the viral capsid (C) protein. The outer host contains 180 copies each of two proteins: the viral membrane (M) protein and the envelope (E) protein (Kostyuchenko et al., 2016; Sirohi et al., 2016). Viral RNA of the Zika virus has been identified in the brain and liver of fetuses and in the brain, eyes, spleen, liver and placenta of pregnant mothers, with the highest viral load existing in the placenta.(Adams Waldorf et al., 2016).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Zika virus RNA
- Property
- PrThr
- Time
- Pt
- System
- Bld
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- ZIKV RNA Bld Ql NAA+probe
- Display Name
- ZIKV RNA NAA+probe Ql (Bld)
- Consumer Name Alpha Get Info
- Zika virus, Blood
Example Answer List: LL1937-3
Source: 3M Health Information Systems| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PresentCopyright http://snomed.info/sct ID:52101004 Present (qualifier value) | LA9633-4 | ||
| AbsentCopyright http://snomed.info/sct ID:2667000 Absent (qualifier value) | LA9634-2 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32774-8 | Zika virus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Zika-Virus RNA: |
| es-ES | Spanish (Spain) | Virus Zika RNA: |
| es-MX | Spanish (Mexico) | ARN del virus del Zika: |
| fr-FR | French (France) | Zika virus ARN: |
| it-IT | Italian (Italy) | Zika virus RNA: Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sangue Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus Zika |
| nl-NL | Dutch (Netherlands) | zikavirus RNA: Synonyms: probe.amp.tar Zika-virus |
| tr-TR | Turkish (Turkey) | Zika virüs RNA: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 寨卡病毒 RNA: Synonyms: 传染毒; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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