91682-5

Histoplasma capsulatum Ab [Identifier] in Cerebral spinal fluid by Immune diffusion (ID)

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Part Description

LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component: Histoplasma capsulatum Ab
Property: Prid
Time: Pt
System: CSF
Scale: Nom
Method: Immune diffusion

Additional Names

Short Name: H capsul Ab CSF ID
Display Name: H. capsulatum Ab Immune diff Nom (CSF)
Consumer Name Alpha Get Info: Histoplasma capsulatum antibody, Spinal fluid

Example Answer List: LL5099-8

Source: Mayo Medical Laboratories

Answer	Code	Score	Answer ID
M band present			LA29407-6
H band present			LA29408-4
H and M bands present			LA29409-2
No band present			LA29410-0

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.66
Last Updated: Version 2.73
Order vs. Observation: Both
Common Test Rank Get Info: 11171

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Histoplasma capsulatum Anticuerpos:Presencia o identidad:Punto temporal:Líquido Cefalorraquideo:Nom:Inmunodifusión
es-MX	Spanish (Mexico)	Histoplasma capsulatum Ab:Presencia o identidad:Punto temporal:Fluído espinal cerebral:Nominal:Difusión inmunitaria (ID)
fr-FR	French (France)	Histoplasma capsulatum Ac:Identification:Ponctuel:Liquide céphalorachidien:Résultat nominal:Immunodiffusion
fr-BE	French (Belgium)	Histoplasma capsulatum Ac:Présence ou identité:Temps ponctuel:LCR:Nominal:Immunodiffusion Synonyms: Anticorps
fr-CA	French (Canada)	Histoplasma capsulatum, Ac:Présence ou identité:Temps ponctuel:LCR:Nominal:Immunodiffusion
it-IT	Italian (Italy)	Histoplasma capsulatum Ab:Prid:Pt:LCS:Nom:Immuno diffusione Synonyms: anticorpo Immuno diffusione (ID) Liquido cerebrospinale Microbiologia Presenza o Identità Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	Histoplasma capsulatum As:identificator:moment:liquor cerebrospinalis:nominaal:immunodiffusie Synonyms: antistof; antilichaam
ru-RU	Russian (Russian Federation)	Histoplasma capsulatum Ат:ПрИд:ТчкВрм:ЦСЖ:Ном:Иммунодиффузия Synonyms: Антитело Иммунодиффузия (ИД) Номинальный;Именной Присутствие или Идентификация Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Histoplazma Kapsulatum Ab:MevcKimlik:Zmlı:BOS:Snf:İmmün difüzyon Synonyms: Ak
uk-UA	Ukrainian (Ukraine)	Histoplasma capsulatum Антитіла:Наявність або Ідентифікація:МоментЧасу:Спинномозкова рідина:Категорійно:Імунодифузія Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Cerebral spinal fluid; Cerebrospinal Fl; H capsul; H capsulatum; H farciminosum; Histo; Histopl; Histoplasma farciminosum; Histoplasmos; Histoplasmosis; ID; Identity or presence; Imm; Immunodiff; Immunodiffusion; Imun; Imune; Microbiology; Nominal; Point in time; Random; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid
zh-CN	Chinese (China)	荚膜组织胞浆菌抗体:存在与否或特征标识:时间点:脑脊液:名义型:免疫扩散法 Synonyms: Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液免疫扩散分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答存在;存在与否;特征标识;身份;身份标识微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间皮疽组织胞浆菌 Ab 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌皮疽组织胞浆菌抗体组织胞浆菌属组织胞浆菌病美洲型组织胞浆菌 Ab 美洲型组织胞浆菌抗体脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液荚膜组织胞浆菌 Ab 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌抗体

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