LOINC
Version 2.72

91783-1Cytomegalovirus [Presence] in Lower respiratory specimen by Organism specific cultureActive

Part Descriptions

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

LP6429-7   Organism specific culture
An organism-specific culture contains nutrients that optimize the growth of a specific organism and inhibitors that prevent the growth of competing organisms. Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus
Property
PrThr
Time
Pt
System
Respiratory.lower
Scale
Ord
Method
Organism specific culture

Additional Names

Short Name
CMV Lower resp Ql Cult
Display Name
CMV Org specific cx Ql (Lower resp)
Consumer Name Alpha
Cytomegalovirus (CMV) culture, Lower respiratory

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Member of these Groups

LG34000-6 Cytomegalovirus|PrThr|Sys:ANYResp

Language Variants Get Info

zh-CNChinese (China)
巨细胞病毒:存在情况或阈值:时间点:呼吸道.下:序数型:微生物特异性培养
nl-NLDutch (Netherlands)
Cytomegalovirus:aanwezigheid:moment:onderste luchtwegen:ordinaal:organisme-specifieke kweek
fr-CAFrench (Canada)
Cytomégalovirus:Présence-Seuil:Temps ponctuel:Système respiratoire.inférieur:Ordinal:Culture spécifique à un microorganisme
fr-FRFrench (France)
Cytomégalovirus:Présence/Seuil:Ponctuel:Voies respiratoires inférieures:Qualitatif:Culture spécifique
it-ITItalian (Italy)
Citomegalovirus:PrThr:Pt:Sistema respiratorio.inferiore:Ord:Organismo, coltura specifica
es-MXSpanish (Mexico)
Citomegalovirus:Presencia o umbral:Punto temporal:Muestra de vías respiratorias inferiores:Ordinal:Cultivo específico del organismo
es-ESSpanish (Spain)
Citomegalovirus:PrThr:Punto temporal:Tracto respiratorio inferior:Ord:Cultivos especíificos
tr-TRTurkish (Turkey)
Cytomegalovirus:MevcEşik:Zmlı:Respiratuvar.alt:Srl:Etken spesifik kültür

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=91783-1