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Part Description

LP111251-7   T-cell receptor excision circle
T cell receptor excision circles (TRECs) are formed as a byproduct of T cell receptor (TCR) generation in the thymus. Every T cell has a unique TCR, and formation of TCRs involves DNA rearrangement into different combinations of variable, diversity, and joining sequences. As these combinations are created, the remaining fragments of excised DNA form circular structures, or TRECs. The number of TRECs is proportional to T cell production, with low TREC numbers being an indicator of inadequate T cell production. In newborns, dried blood spot TREC analysis is used to screen for severe combined immunodeficiency as well as other disorders associated with low T cell counts, such as DiGeorge syndrome, trisomy 21, CHARGE syndrome, and congenital leukemia. PMID: 25937517 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
T-cell receptor excision circle:ThreshNum:Pt:Bld.dot:Qn:
Long Common Name
T-cell receptor excision circle [Cycle Threshold #] in DBS
Short Name
TREC ThreshNum DBS Qn
Display Name
T-cell receptor excision circle (DBS) [ThreshNum]
Consumer Name Alpha Get Info
T-cell receptor excision circle, Dried blood spot

Part Model Get Info

  • Component
    T-cell receptor excision circle
    LP111251-7
    • Analyte
      T-cell receptor excision circle
      LP111251-7
      • Component Numerator
        T-cell receptor excision circle
        LP111251-7
        • Component Numerator Core
          T-cell receptor excision circle
          LP111251-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ThreshNum
    LP188772-0
  • Time
    Pt
    LP6960-1
  • System
    Bld.dot
    LP21304-8
    • System Core
      Bld.dot
      LP21304-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
54089-8Newborn screening panel American Health Information Community (AHIC)
62333-0Severe combined immunodeficiency (SCID) newborn screening panel

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)T-cell receptor excision circle (TREC):Prahová hodnota:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GRGreek (Greece)Κύκλος αποκοπής υποδοχέων Τ-κυττάρων:ThreshNum:Pt:Bld.dot:Qn:
Synonyms: Bld.dot CHEM Pt Qn ThreshNum Αίμα Κύκλος αποκοπής υποδοχέων Τ-κυττάρων Τ-κύτταρο
es-ESSpanish (Spain)Círculos de escisión del receptor de células T:ThreshNnum:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Círculo de escisión del receptor de células T:ThreshNum:Punto temporal:DBS:Cuantitativo:
fr-FRFrench (France)Récepteur cellules T cercle d'excision:Cycle seuil:Ponctuel:Sang buvard:Numérique:
it-ITItalian (Italy)Linfocita T, circolo di escissione recettore:Thresnum:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Circolo di escissione di recettore di linfocita T Limite di soglia Linfocita T Punto nel tempo (episodio) Sangue Spot sangue secco
nl-NLDutch (Netherlands)T-celreceptor excisiecirkel:drempelwaarde nummer:moment:gedroogde bloedspot:kwantitatief:
tr-TRTurkish (Turkey)T-hücresi reseptörü excision circle:EşikDeğ:Zmlı:Kan.nokta:Kant:
Synonyms: Eşik Değer
zh-CNChinese (China)T-细胞受体重排删除环:阈值循环圈数:时间点:全血.斑点:定量型:
Synonyms: T 细胞;UCHL-1 T-細胞受體重排刪除環;T-細胞受體切除環;T-细胞受体重排删除环;T-细胞受体重排切割环;T-cell receptor excision circle;TREC;T cell receptor rearrangement excision circle 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值 血;血液

Example Units

UnitSource
{Ct_value}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92006-6