92673-3
Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma
Active
69845-6 2-Hydroxyglutarate [Moles/volume] in Serum or Plasma
Part Descriptions
LP18403-3 2-Hydroxyglutarate
alpha-Hydroxyglutaric acid (2-hydroxyglutaric acid) is an alpha hydroxy acid. In humans the compound is formed by a Hydroxyacid-oxoacid transhydrogenase whereas in bacteria is formed by a 2-hydroxyglutarate synthase. The compound can be converted to alpha-Ketoglutaric acid through the action of a 2-hydroxyglutarate dehydrogenase which, in humans, are two enzymes called D2HGDH and L2HGDH. Deficiency in either of these two enzymes lead to a disease known as 2-Hydroxyglutaric aciduria.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- 2-Hydroxyglutarate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 2OH-gluterate SerPl-sCnc
- Display Name
- 2-Hydroxyglutarate [Moles/Vol]
- Consumer Name Alpha Get Info
- 2-Hydroxyglutarate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 18703
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 92673-3 | Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | 2-Hidroxiglutarato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 2-hidroxiglutarato: |
| et-EE | Estonian (Estonia) | 2-hüdroksüglutaraat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | 2-hydroxyglutarate: |
| fr-BE | French (Belgium) | 2-hydroxyglutarate: |
| fr-CA | French (Canada) | 2-hydroxyglutarate: |
| it-IT | Italian (Italy) | 2-Idrossiglutarato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | 2-hydroxyglutaraat: |
| pt-BR | Portuguese (Brazil) | 2-Hidroxiglutarato: |
| ru-RU | Russian (Russian Federation) | 2-Гидроксиглутарат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | 2-Hidroksiglutarat: |
| zh-CN | Chinese (China) | 2-羟基戊二酸: Synonyms: 2-OH-戊二酸 Ⅱ II 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
69851-4 3-Hydroxyglutarate [Moles/volume] in Serum or Plasma
Part Descriptions
LP18415-7 3-Hydroxyglutarate
3-hydroxyglutaric acid (3-OH-GA) is an important metabolite in glutaryl co-enzyme A dehydrogenase (GCDH) deficiency and considered to be a potential neurotoxin. Increased levels of 3-OH-GA is thought to be a biochemical risk factor for neurodegeneration in GCDH deficiency. PMID: 16573641
Source: Regenstrief LOINC, PMID: 16573641
Fully-Specified Name
- Component
- 3-Hydroxyglutarate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 3OH-Glutarate SerPl-sCnc
- Display Name
- 3-Hydroxyglutarate [Moles/Vol]
- Consumer Name Alpha Get Info
- 3-Hydroxyglutarate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 18134
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 92673-3 | Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | 3-Hidroxiglutarato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 3-hidroxiglutarato: |
| et-EE | Estonian (Estonia) | 3-hüdroksüglutaraat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | 3-hydroxyglutarate: |
| fr-BE | French (Belgium) | 3-hydroxyglutarate: |
| fr-CA | French (Canada) | 3-hydroxyglutarate: |
| it-IT | Italian (Italy) | 3-Idrossiglutarato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | 3-hydroxyglutaraat: |
| pt-BR | Portuguese (Brazil) | 3-Hidroxiglutarato: |
| ru-RU | Russian (Russian Federation) | 3-Гидроксиглутарат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | 3-Hidroksiglutarat: |
| zh-CN | Chinese (China) | 3-羟基戊二酸: Synonyms: 3-OH-戊二酸 Ⅲ III 三 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
27301-1 Glutarate [Moles/volume] in Serum or Plasma
Part Descriptions
LP18437-1 Glutarate
Glutaric acid (IUPAC systematic name:pentanedioic acid) is a simple five-carbon linear dicarboxylic acid.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Glutarate (Wikipedia)
LP18437-1 Glutarate
Glutaric acid (glutarate) is a simple five-carbon linear dicarboxylic acid. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutaric acid to gross organic aciduria occurs in Glutaric aciduria. Glutaric aciduria type 1 is an autosomal-recessive disorder resulting from a deficiency of mitochondrial glutaryl-CoA dehydrogenase (EC 1.3.99.7, GCDH) which is involved in the metabolism of lysine, hydroxylysine, and tryptophan. Glutaric aciduria type I lead to nonspecific developmental delay, hypotonia, and macrocephaly with cerebral atrophy of prenatal onset. Treatment is mainly based on restriction of lysine intake, supplementation of carnitine, and an intensification of therapy during intercurrent illnesses. The major principle of dietary treatment is to reduce the production of glutaric acid and 3-hydroxyglutaric acid by restriction of natural protein in general and of lysine in particular. PMID: 17465389, PMID: 15505398
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
Fully-Specified Name
- Component
- Glutarate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Glutarate SerPl-sCnc
- Display Name
- Glutarate [Moles/Vol]
- Consumer Name Alpha Get Info
- Glutarate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9553
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 92673-3 | Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG48714-6 | Glutarate| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Glutarato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Glutarato: |
| es-AR | Spanish (Argentina) | glutarato: |
| et-EE | Estonian (Estonia) | Glutaraat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Glutarate: |
| fr-FR | French (France) | Glutarate: |
| fr-CA | French (Canada) | Glutarate: |
| it-IT | Italian (Italy) | Glutarato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 글루타르산: |
| nl-NL | Dutch (Netherlands) | glutaraat: |
| pt-BR | Portuguese (Brazil) | Glutarato: Synonyms: Pentanedioic acid; |
| ru-RU | Russian (Russian Federation) | Глутарат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | glutarat: |
| zh-CN | Chinese (China) | 戊二酸: Synonyms: 克分子浓度; |
Example Units
| Unit | Source |
|---|---|
| nmol/mL | Example UCUM Units |
79476-8 Ethylmalonate [Moles/volume] in Serum or Plasma
Part Descriptions
LP15563-7 Ethylmalonate
Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Ethylmalonic acid
Fully-Specified Name
- Component
- Ethylmalonate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Ethylmalonate SerPl-sCnc
- Display Name
- Ethylmalonate [Moles/Vol]
- Consumer Name Alpha Get Info
- Ethylmalonate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17991
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 92673-3 | Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Malonato de etilo: |
| es-ES | Spanish (Spain) | Etilmalonato: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Etüülmalonaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | Éthylmalonate: |
| fr-BE | French (Belgium) | Malonate de diéthyle: |
| fr-CA | French (Canada) | Malonate de diéthyle: |
| it-IT | Italian (Italy) | Etilmalonato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | ethylmalonaat: |
| ru-RU | Russian (Russian Federation) | Этилмалонат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Etilmalonat: |
| zh-CN | Chinese (China) | 乙基丙二酸: Synonyms: EMA; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
69829-0 Methylsuccinate [Moles/volume] in Serum or Plasma
Part Descriptions
LP18443-9 Methylsuccinate
Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy [OMIM: 602473], a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea. PMID: 12382164
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Human Metabolome Database (Methylsuccinic acid)
Fully-Specified Name
- Component
- Methylsuccinate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Me-succinate SerPl-sCnc
- Display Name
- Methylsuccinate [Moles/Vol]
- Consumer Name Alpha Get Info
- Methylsuccinate, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19466
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 92673-3 | Hydroxyglutarates and glutarate and ethylmalonate and methylsuccinate panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Metilsuccinato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Succinato de metilo: |
| et-EE | Estonian (Estonia) | Metüülsuksinaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | 2-méthylsuccinate: |
| fr-BE | French (Belgium) | Méthylsuccinate: |
| fr-CA | French (Canada) | Méthylsuccinate: |
| it-IT | Italian (Italy) | Metilsuccinato: Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | methylsuccinaat: |
| pt-BR | Portuguese (Brazil) | Metilsuccinato: |
| ru-RU | Russian (Russian Federation) | Метилсукцинат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Metilsüksinat: |
| zh-CN | Chinese (China) | 甲基琥珀酸: Synonyms: 2-甲基丁二酸; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |