92806-9
Keratan sulfate/Creatinine [Ratio] in Urine
Active
Part Descriptions
LP14490-4 Keratan sulfate
A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.
Source: National Library of Medicine, MeSH 2006
LP14490-4 Keratan sulfate
Keratan sulfate (KS) is one of the glycosaminoglycans found primarily in the cornea, nervous tissue, and bone. When the enzyme that breaks down KS is deficient or absent, KS accumulates in lysosomes which results in cell, tissue, and organ dysfunction. The lysosomal storage disorders are known as mucopolysaccharidoses (MPS) and can involve impaired enzymatic function that blocks the catabolism of any of the glycosaminoglycans, including dermatan sulfate, heparin sulfate, keratan sulfate, chondroitin sulfate, or hyaluronan. MPS due to the accumulation of any one or more glycosaminoglycans have many symptoms in common including a chronic or progressive course, multisystem involvement, organomegaly, dysostosis multiplex, abnormal facies, affected hearing, affected vision, affected airway, cardiovascular issues, profound mental retardation, and joint mobility difficulties. MPS can be diagnosed by testing for the deficient or absent enzyme. Enzyme replacement therapy is used to monitor treatment.[https://ommbid.mhmedical.com/content.aspx?bookid=971§ionid=62642135]
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Keratan sulfate/Creatinine
- Property
- Ratio
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Keratan Sulfate/Creat Ur-Rto
- Display Name
- Keratan sulfate/Creatinine (U) [Ratio]
- Consumer Name Alpha Get Info
- Keratan sulfate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
94691-3 | Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine |
105125-9 | Lysosomal storage disorders screen panel - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Queratán sulfato/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Sulfato de queratán / Creatinina: |
et-EE | Estonian (Estonia) | Kerataansulfaat/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-FR | French (France) | Kératane sulfate/créatinine: |
fr-CA | French (Canada) | Sulfate de kératane/Créatinine: |
fr-BE | French (Belgium) | Sulfate de kératane/Créatinine: Synonyms: SO4 |
it-IT | Italian (Italy) | Cheratan solfato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | keratansulfaat/creatinine: Synonyms: kreatinine |
ru-RU | Russian (Russian Federation) | Кератансульфат/Креатинин: Synonyms: Количественный Коэффициент; |
tr-TR | Turkish (Turkey) | Keratan sülfat/Kreatinin: |
zh-CN | Chinese (China) | 硫酸角质素/肌酐: Synonyms: CR; |
Example Units
Unit | Source |
---|---|
mg/mmol{creat} | Example UCUM Units |
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