Version 2.77

Part Descriptions

LP343942-1   MET gene copy number
MET gene amplification studies evaluate the number of copies of the MET gene present in a single cell. Amplification is determined based on the MET gene copy number and MET to centromere ratio. Different criteria have been proposed for what constitutes amplification, including a MET to centromere ratio of >= 2, an average MET gene copy number >=5, and at least 15 gene copies in 10% of the tumor cell nuclei that were counted. MET amplification is associated with worse prognosis in a variety of cancers, including non-small cell lung and gastroesophageal cancer. PMID: 27926778 Source: Regenstrief LOINC

LP343942-1   MET gene copy number
The ratio of MET signals per nucleus to chromosome 7 signals per nucleus is used to determine if MET gene amplification has occurred. MET amplification is a biomarker for different types of cancer, including non-small cell lung cancer. Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
MET gene copy number/nucleus
Property
EntNum
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
MET copy num/nucleus EntNum Bld/T FISH
Display Name
MET copy num/nucleus FISH (Bld/Tiss) [Entitic number]
Consumer Name Alpha Get Info
MET copy number/nucleus, Blood or tissue specimen

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Número de copia del gen MET/núcleo:Número entítico:Punto temporal:Sangre o tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Número de copia / núcleo del gen MET:Número entitic:Punto temporal:Sangre o tejido:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) MET gène nombre de copie/noyaux:Nombre/entité:Ponctuel:Sang/Tissu:Numérique:FISH
it-IT Italian (Italy) MET, numero copia del gene/nucleo:EntNum:Pt:Sangue/Tess:Qn:FISH
Synonyms: Gene MET Ibridazione in situ fluorescente (FISH) Numero copia del gene MET Numero entitico Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) aantal kopieën van MET-gen/kern:aantal/eenheid:moment:bloed of weefsel:kwantitatief:FISH
Synonyms: MET nucleus
zh-CN Chinese (China) MET 基因拷贝数/核:实体数量:时间点:全血/组织:定量型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 MET 基因拷贝（副本）数（数量、计数） 个数;数目 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 细胞核 血;血液 遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit Source
{#} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92906-7