93238-4
dRVVT excess phospholipid in Platelet poor plasma by Coagulation assay --post heparin neutralization
Active
Term Description
Confirmatory dRVVT measured after heparin neutralization, which removes the effects of any heparin that may be present in the sample. Heparin neutralization methods include the addition of heparinase, an enzyme that breaks down heparin, and heparin adsorption, in which a substance is added that binds the heparin that is present.
Source: Regenstrief LOINC
Part Descriptions
LP411053-4 post heparin neutralization
The "post heparin neutralization" challenge in LOINC includes a variety of methods to remove the effect of heparin from a sample before testing. These methods include the addition of heparinase, an enzyme that breaks down heparin, and heparin adsorption, in which a substance is added that binds the heparin that is present.
Source: Regenstrief LOINC
LP65493-6 Coagulation dilute Russell viper venom induced.excess phospholipid
Dilute Russell viper venom time (dRVVT) is a screening laboratory test for detecting the presence of lupus anticoagulants (LA), which are autoantibodies associated with excess clot formation, excess bleeding, and repeated miscarriages. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. If phospholipid antibodies are present, this reaction will be inhibited, which will prolong the screening dRVVT and suggests the presence of LA. A confirmatory dRVVT test measures dRVVT in the presence of excess phospholipid, which saturates the antibody binding sites and thereby diminishes the inhibitory effect of the LA, resulting in a normalization of the dRVVT. The dRVVT screen to confirm ratio is calculated as Screen dRVVT/Confirm dRVVT, and the dRVVT percent correction is calculated as [(Screen dRVVT - Confirm dRVVT)/Screen dRVVT]x100. PMID: 19624461
Source: Regenstrief LOINC, PMID: 19624461
LP21280-0 Dilute Russell viper venom time
Dilute Russell's viper venom time (dRVVT) is a laboratory test for lupus anticoagulant (LA). This in vitro diagnostic test is based on the property that the venom of the Russell's Viper is effective at inducing thrombosis. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid. The dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an autoimmune disorder), because it is not influenced by deficiencies in clotting factors VIII, IX or XI. The dRVVT is thought to be more sensitive than the activated partial thromboplastin time (aPTT) for detection of lupus anticoagulants.
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Source: Wikipedia, Dilute Russell viper venom time (Wikipedia)
Fully-Specified Name
- Component
- Coagulation dilute Russell viper venom induced.excess phospholipid^post heparin neutralization
- Property
- Time
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Coag
Additional Names
- Short Name
- dRVVT confirm p hep neut PPP
- Display Name
- dRVVT excess phospholipid post heparin neutralization Coag (PPP) [Time]
- Consumer Name Alpha Get Info
- dRVVT excess phospholipid after heparin neutralization, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.67
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75515-7 | Lupus anticoagulant aPTT and dRVVT screening panel W Reflex |
| 75881-3 | Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Coagulación inducida por el veneno de vibora de Russell diluido. Exceso de fosfolípido^Pos neutralización de heparina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | La coagulación diluye el veneno de la víbora de Russell inducida. Exceso de fosfolípidos ^ después de la neutralización de la heparina.: |
| fr-FR | French (France) | Temps de venin vipère Russell dilué en excès de phospholipides après neutralisation à l'héparine: |
| it-IT | Italian (Italy) | Coagulazione indotta da veleno diluito di vipera Russell.fosfolipidi in eccesso^post neutralizzazione di eparina: Synonyms: Neutralizzazione dell''eparina Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione Tempo (e.g. secondi) Tempo di veleno diluito di vipera Russel (dRVVT) Tempo di veleno diluito di vipera Russel (dRVVT) f Test di coagulazione |
| zh-CN | Chinese (China) | 稀释蝰蛇毒诱导型凝血过程.过量磷脂^在肝素中和之后: Synonyms: CRVV DDRVTVT dRVV dRVV 时间; |
Example Units
| Unit | Source |
|---|---|
| s | Example UCUM Units |
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